Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 8/20 | 0.44 |
| ▸ | CA1 | P00915 | 7/20 | 0.44 |
| ▸ | CA12 | O43570 | 6/20 | 0.44 |
| ▸ | CA9 | Q16790 | 6/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.44 |
| ▸ | TLR4 | O00206 | 2/20 | 0.43 |
| ▸ | ANTXR2 | P58335 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16500346 | 1.00 | MAPT (0.49) | MAPTCYP2D6THRBHSD17B10CA2 | |
| SCHEMBL13621251 | 1.00 | MAPT (0.49) | MAPTCYP2D6THRBHSD17B10CA2 | |
| SCHEMBL3334421 | 1.00 | MAPT (0.49) | MAPTCYP2D6THRBHSD17B10CA2 | |
| SCHEMBL20582014 | 1.00 | MAPT (0.49) | MAPTCYP2D6THRBHSD17B10CA2 | |
| SCHEMBL16500298 | 1.00 | MAPT (0.49) | MAPTCYP2D6THRBHSD17B10CA2 | |
| SCHEMBL19079629 | 0.98 | MAPT (0.47) | MAPTCYP2D6THRBHSD17B10CA2 | |
| SCHEMBL22107783 | 0.96 | MAPT (0.46) | MAPTCYP2D6THRBHSD17B10CA2 | |
| SCHEMBL22034432 | 0.93 | MAPT (0.44) | MAPTCYP2D6THRBHSD17B10CA2 | |
| SCHEMBL22034455 | 0.92 | MAPT (0.43) | MAPTCYP2D6THRBHSD17B10CA2 | |
| SCHEMBL22076451 | 0.91 | MAPT (0.47) | MAPTCYP2D6THRBHSD17B10CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315532-B2 | Fatty acid carbohydrate hybrid molecules as therapeutic agents and methods thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-04-19 | — | — | US | disclosed |
| US-20100144653-A1 | Fatty acid carbohydrate hybrid molecules as therapeutic agents and methods thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2010-06-10 | — | — | US | disclosed |
| WO-2006127977-A1 | FATTY ACID CARBOHYDRATE HYBRID MOLECULES AS THERAPEUTIC AGENTS AND METHODS THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2006-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144653-A1 | Fatty acid carbohydrate hybrid molecules as therapeutic agents and methods thereof | FASN, FABP1, FABP2 | MAPT 2687/4885CYP2D6 3526/4885THRB 3251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.