SCHEMBL333637

SCHEMBL333637

CCCCCCCC(=O)CCC(S)[Si](OC)(OC)OC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.47
MAPT P10636 1/20 0.47
LMNA P02545 2/20 0.40
HAO1 Q9UJM8 1/20 0.40
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
FFAR4 Q5NUL3 2/20 0.39
FFAR1 O14842 2/20 0.39
PPARG P37231 6/20 0.38
PPARD Q03181 6/20 0.38
PPARA Q07869 6/20 0.38
GPR84 Q9NQS5 5/20 0.38
HDAC11 Q96DB2 5/20 0.38
TSHR P16473 4/20 0.38
ALDH1A1 P00352 2/20 0.38
TLR2 O60603 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
FABP4 P15090 2/20 0.38
PTPN1 P18031 2/20 0.38
SLC22A6 Q4U2R8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL334574 0.85 KMT2A (0.46) KMT2AMAPTLMNAHAO1CES2
SCHEMBL333548 0.85 KMT2A (0.46) KMT2AMAPTLMNAHAO1CES2
SCHEMBL19410710 0.80 ZDHHC7 (0.37) LMNAGPR84TSHR
SCHEMBL2979460 0.80 ZDHHC7 (0.37) LMNAGPR84TSHR
SCHEMBL11783477 0.80 ZDHHC7 (0.37) LMNAGPR84TSHR
SCHEMBL989249 0.80 ZDHHC7 (0.37) LMNAGPR84TSHR
SCHEMBL10324721 0.80 ZDHHC7 (0.37) LMNAGPR84TSHR
SCHEMBL3688687 0.80 ZDHHC7 (0.37) LMNAGPR84TSHR
SCHEMBL20576622 0.80 ZDHHC7 (0.37) LMNAGPR84TSHR
SCHEMBL2985541 0.80 ZDHHC7 (0.37) LMNAGPR84TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1560836-B1 PROCESS FOR MANUFACTURE OF BLOCKED MERCAPTOSILANE COUPLING AGENTS MOMENTIVE PERFORMANCE MAT INC (US) 2015-12-30 EP disclosed
US-8097743-B2 Process for manufacture of blocked mercaptosilane coupling agents MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-01-17 US disclosed
US-20050245754-A1 Process for manufacture of blocked mercaptosilane coupling agents MOMENTIVE PERFORMANCE MATERIALS INC. 2005-11-03 US disclosed
EP-1560836-A1 PROCESS FOR MANUFACTURE OF BLOCKED MERCAPTOSILANE COUPLING AGENTS GENERAL ELECTRIC COMPANY (US) 2005-08-10 EP disclosed
WO-2005007660-A1 PROCESS FOR MANUFACTURE OF BLOCKED MERCAPTOSILANE COUPLING AGENTS GENERAL ELECTRIC COMPANY (US) 2005-01-27 WO disclosed