SCHEMBL3336743

SCHEMBL3336743

C=CC[Si](CCCCCC)(OCC)OCC

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.40
ALDH1A1 P00352 2/20 0.33
FAAH O00519 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.32
ZDHHC2 Q9UIJ5 1/20 0.32
THRB P10828 1/20 0.31
DNM1 Q05193 4/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5412372 0.92 TSHR (0.36) TSHRALDH1A1
SCHEMBL5401229 0.84 TSHR (0.31) TSHR
SCHEMBL11729323 0.82
SCHEMBL3339180 0.82 TSHR (0.41) TSHRALDH1A1FAAHZDHHC20ZDHHC2
SCHEMBL2122621 0.81 TSHR (0.42) TSHRALDH1A1THRBDNM1MEN1
SCHEMBL2122966 0.81 TSHR (0.42) TSHRALDH1A1THRBDNM1MEN1
SCHEMBL2122736 0.81 TSHR (0.42) TSHRALDH1A1THRBDNM1MEN1
SCHEMBL15847402 0.81 TSHR (0.42) TSHRALDH1A1THRBDNM1MEN1
SCHEMBL2119690 0.81 TSHR (0.42) TSHRALDH1A1THRBDNM1MEN1
SCHEMBL2123739 0.81 TSHR (0.42) TSHRALDH1A1THRBDNM1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968458-B2 Composition for resist underlayer film and process for producing same JSR CORPORATION (JP) 2015-03-03 US disclosed
US-8808446-B2 Composition for resist underlayer film and process for producing same JSR CORPORATION (JP) 2014-08-19 US disclosed
CN-101133364-B Composition for resist underlayer film and method for producing same JSR CORP 2013-03-20 CN disclosed
US-20100151384-A1 COMPOSITION FOR RESIST UNDERLAYER FILM AND PROCESS FOR PRODUCING SAME JSR CORPORATION (JP) 2010-06-17 US disclosed
US-20090050020-A1 COMPOSITION FOR RESIST UNDERLAYER FILM AND PROCESS FOR PRODUCING SAME JSR CORPORATION (JP) 2009-02-26 US disclosed
CN-101133364-A Composition for resist underlayer film and method for producing same JSR CORP (JP) 2008-02-27 CN disclosed
EP-1855159-A1 COMPOSITION FOR UNDERLAYER FILM OF RESIST AND PROCESS FOR PRODUCING THE SAME JSR Corporation (JP) 2007-11-14 EP disclosed