Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 6/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CCND3 | P30281 | 3/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.35 |
| ▸ | CDK4 | P11802 | 2/20 | 0.35 |
| ▸ | CCND1 | P24385 | 2/20 | 0.35 |
| ▸ | CCND2 | P30279 | 2/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33378033 | 0.85 | CYP17A1 (0.36) | CHEK1CDK2MAPKAPK2GSK3BCCNA2 | |
| SCHEMBL33378006 | 0.85 | CDK2 (0.36) | CHEK1CDK2MAPKAPK2CSNK2A2GSK3B | |
| SCHEMBL33377902 | 0.85 | CDK2 (0.35) | CHEK1CDK2MAPKAPK2CSNK2A2GSK3B | |
| SCHEMBL33378038 | 0.83 | CHEK1 (0.43) | CHEK1CDK2CSNK2A2GSK3BCCNA2 | |
| SCHEMBL33378044 | 0.81 | GRM5 (0.39) | CDK2CSNK2A2GSK3BKDRGRM5 | |
| SCHEMBL33377947 | 0.80 | KDM4E (0.42) | GSK3BKMT2A | |
| SCHEMBL33377992 | 0.80 | CDK2 (0.36) | CDK2MAPKAPK2CSNK2A2GSK3BTYK2 | |
| SCHEMBL33377998 | 0.80 | GSK3B (0.40) | CDK2MAPKAPK2GSK3B | |
| SCHEMBL22413270 | 0.78 | CDK2 (0.41) | CDK2MAPKAPK2GSK3BMEN1KMT2A | |
| SCHEMBL19742549 | 0.78 | CDK2 (0.57) | CDK2MAPKAPK2CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4717312-A1 | PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2026-04-01 | — | — | EP | disclosed |