Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28015487 | 0.92 | TSHR (0.50) | TSHRSMN1; SMN2DNM1ALDH1A1TDP1 | |
| SCHEMBL7007183 | 0.88 | — | — | |
| SCHEMBL103963 | 0.83 | — | — | |
| SCHEMBL9812301 | 0.83 | TSHR (0.44) | TSHRSMN1; SMN2DNM1FDPSLMNA | |
| SCHEMBL28184120 | 0.83 | TSHR (0.44) | TSHRSMN1; SMN2DNM1FDPSLMNA | |
| SCHEMBL9487774 | 0.83 | TSHR (0.44) | TSHRSMN1; SMN2DNM1FDPSLMNA | |
| SCHEMBL23924957 | 0.80 | TSHR (0.50) | TSHRSMN1; SMN2DNM1ALDH1A1TDP1 | |
| SCHEMBL4283686 | 0.80 | TSHR (0.50) | TSHRSMN1; SMN2DNM1ALDH1A1TDP1 | |
| SCHEMBL4268912 | 0.80 | TSHR (0.50) | TSHRSMN1; SMN2DNM1ALDH1A1TDP1 | |
| SCHEMBL23924958 | 0.80 | TSHR (0.50) | TSHRSMN1; SMN2DNM1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100143273-A1 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE APROTIC HYDROCARBON-BASED VOLATILE SOLVENT | L'OREAL S.A. (FR) | 2010-06-10 | — | — | US | disclosed |
| EP-2083789-A1 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE APROTIC HYDROCARBON-BASED VOLATILE SOLVENT | L'Oréal (FR) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008061985-A1 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE APROTIC HYDROCARBON-BASED VOLATILE SOLVENT | L'OREAL (FR) | 2008-05-29 | — | — | WO | disclosed |
| EP-1591466-A1 | Preparation of a polyether composition | BASF AKTIENGESELLSCHAFT (DE) | 2005-11-02 | — | — | EP | disclosed |