Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 6/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2307301 | 0.96 | FGFR1 (0.60) | FGFR1GAAKDRALDH1A1HPGD | |
| SCHEMBL3342348 | 0.90 | GAA (0.65) | FGFR1GAAKDRALDH1A1HPGD | |
| SCHEMBL12135737 | 0.89 | GAA (0.64) | FGFR1GAAKDRALDH1A1HPGD | |
| SCHEMBL2308834 | 0.88 | GAA (0.52) | FGFR1GAAKDRALDH1A1HPGD | |
| SCHEMBL2308483 | 0.88 | GAA (0.73) | FGFR1GAAALDH1A1HPGDMAPT | |
| Hydrochloric Acid SCHEMBL2309577 | 0.87 | GAA (0.71) | FGFR1GAAALDH1A1HPGDMAPT | |
| SCHEMBL13304851 | 0.86 | GAA (0.59) | FGFR1GAAALDH1A1HPGDMAPT | |
| SCHEMBL2305621 | 0.84 | GAA (0.52) | FGFR1GAAKDRALDH1A1HPGD | |
| SCHEMBL13304855 | 0.82 | GAA (0.59) | FGFR1GAAALDH1A1HPGDMAPT | |
| SCHEMBL13304847 | 0.82 | GAA (0.67) | FGFR1GAAKDRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012217-B2 | Benzimidazole compounds differentiate a mammalian stem cell into mesodermal or cardiomyocyte cells | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2015-04-21 | — | — | US | disclosed |
| US-9012217-B2 | Benzimidazole compounds differentiate a mammalian stem cell into mesodermal or cardiomyocyte cells | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2015-04-21 | — | — | US | disclosed |
| US-9012217-B2 | Benzimidazole compounds differentiate a mammalian stem cell into mesodermal or cardiomyocyte cells | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2015-04-21 | — | — | US | disclosed |
| US-20100159596-A1 | SMALL MOLECULE COMPOUNDS FOR STEM CELL DIFFERENTIATION | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-06-24 | — | — | US | disclosed |
| US-20100159596-A1 | SMALL MOLECULE COMPOUNDS FOR STEM CELL DIFFERENTIATION | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-06-24 | — | — | US | disclosed |
| US-20100159596-A1 | SMALL MOLECULE COMPOUNDS FOR STEM CELL DIFFERENTIATION | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100159596-A1 | SMALL MOLECULE COMPOUNDS FOR STEM CELL DIFFERENTIATION | RCOR3, BRD3, BRPF3 | FGFR1 102/4885GAA 4544/4885KDR 2632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.