Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 8/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19477967 | 0.94 | CYP2C19 (0.40) | TLR2CYP2C19EPHX2KDM4EMAPK1 | |
| SCHEMBL19472457 | 0.87 | CYP2C19 (0.36) | TLR2CYP2C19EPHX2KDM4EMAPK1 | |
| SCHEMBL19472458 | 0.86 | TLR2 (0.37) | TLR2S1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL24495946 | 0.86 | CYP2C19 (0.42) | CYP2C19EPHX2KDM4EMAPK1HIF1A | |
| SCHEMBL7645968 | 0.84 | S1PR2 (0.44) | KDM4EMAPK1HIF1AS1PR2S1PR4 | |
| SCHEMBL21383587 | 0.84 | S1PR2 (0.44) | KDM4EMAPK1HIF1AS1PR2S1PR4 | |
| SCHEMBL5052645 | 0.84 | S1PR2 (0.44) | KDM4EMAPK1HIF1AS1PR2S1PR4 | |
| SCHEMBL13862877 | 0.84 | CYP2C19 (0.41) | CYP2C19EPHX2KDM4EMAPK1HIF1A | |
| SCHEMBL3346379 | 0.83 | CA12 (0.44) | TLR2CYP2C19EPHX2CA12CA1 | |
| SCHEMBL5053958 | 0.82 | S1PR2 (0.42) | KDM4EMAPK1HIF1AS1PR2S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160485-A1 | Hydrolysis stable self-etching, self-priming adhesive | KLEE JOACHIM | 2010-06-24 | — | — | US | disclosed |
| US-20100160485-A1 | Hydrolysis stable self-etching, self-priming adhesive | KLEE JOACHIM | 2010-06-24 | — | — | US | disclosed |
| US-20100160485-A1 | Hydrolysis stable self-etching, self-priming adhesive | KLEE JOACHIM | 2010-06-24 | — | — | US | disclosed |
| US-20080194730-A1 | Hydrolysis stable self-etching, self-priming adhesive | KLEE JOACHIM | 2008-08-14 | — | — | US | disclosed |
| US-20080194730-A1 | Hydrolysis stable self-etching, self-priming adhesive | KLEE JOACHIM | 2008-08-14 | — | — | US | disclosed |
| US-20080194730-A1 | Hydrolysis stable self-etching, self-priming adhesive | KLEE JOACHIM | 2008-08-14 | — | — | US | disclosed |
| EP-1437999-B1 | HYDROLYSIS STABLE SELF-ETCHING, SELF-PRIMING ADHESIVE | DENTSPLY DETREY GMBH (DE) | 2006-12-20 | — | — | EP | disclosed |
| US-20040266906-A1 | Hydrolysis stable self-etching,self-priming adhesive | KLEE JOACHIM (DE) | 2004-12-30 | — | — | US | disclosed |
| EP-1437999-A1 | HYDROLYSIS STABLE SELF-ETCHING, SELF-PRIMING ADHESIVE | DENTSPLY DETREY GmbH (DE) | 2004-07-21 | — | — | EP | disclosed |
| WO-2003035013-A1 | HYDROLYSIS STABLE SELF-ETCHING, SELF-PRIMING ADHESIVE | DENTSPLY DETREY GMBH (DE) | 2003-05-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194730-A1 | Hydrolysis stable self-etching, self-priming adhesive | PPA1, PHOSPHO1, PDAP1 | TLR2 3282/4885CYP2C19 3294/4885EPHX2 118/4885 |
| US-20100160485-A1 | Hydrolysis stable self-etching, self-priming adhesive | PPA1, PHOSPHO1, PDAP1 | TLR2 3282/4885CYP2C19 3294/4885EPHX2 118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.