⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1888612 | 0.93 | TSHR (0.52) | — | |
| SCHEMBL7738560 | 0.91 | TSHR (0.56) | — | |
| SCHEMBL6347396 | 0.91 | TSHR (0.56) | — | |
| SCHEMBL10880422 | 0.85 | — | — | |
| SCHEMBL15546954 | 0.79 | TSHR (0.39) | — | |
| SCHEMBL6336602 | 0.78 | TRPV1 (0.47) | — | |
| SCHEMBL6482680 | 0.77 | TSHR (0.61) | — | |
| SCHEMBL9868995 | 0.74 | TSHR (0.33) | — | |
| SCHEMBL6401929 | 0.74 | — | — | |
| SCHEMBL782616 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100143421-A1 | Delivery Device | DOW CORNING EUROPE SA (BE) | 2010-06-10 | — | — | US | disclosed |
| EP-2004737-A1 | DELIVERY DEVICE | Dow Corning Corporation (US) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007118816-A1 | DELIVERY DEVICE | DOW CORNING CORPORATION (US) | 2007-10-25 | — | — | WO | disclosed |
| EP-0643685-A1 | PALLADIUM CATALYZED ADDITION OF AMINES TO 3,4-EPOXY-1-BUTENE. | EASTMAN CHEM CO (US) | 1995-03-22 | — | — | EP | disclosed |
| EP-0178165-B1 | SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL | KONICA CORPORATION (JP) | 1989-03-01 | — | — | EP | disclosed |
| US-4623617-A | MAGENTA COUPLER AND S TABILIZER | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1986-11-18 | — | — | US | disclosed |
| EP-0178165-A1 | Silver halide color photographic material | KONICA CORPORATION (JP) | 1986-04-16 | — | — | EP | disclosed |