Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.47 |
| ▸ | PPARA | Q07869 | 12/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3280234 | 0.91 | FFAR1 (0.56) | PPARGPPARAFFAR1KDR | |
| SCHEMBL3279604 | 0.90 | PPARG (0.56) | PPARGPPARA | |
| SCHEMBL3283709 | 0.72 | FFAR1 (0.61) | PPARGPPARAFFAR1KDR | |
| SCHEMBL3284439 | 0.71 | PPARG (0.61) | PPARGPPARA | |
| SCHEMBL3279823 | 0.71 | FFAR1 (0.62) | PPARGPPARAFFAR1KDR | |
| SCHEMBL8340638 | 0.70 | KDR (0.50) | PPARGPPARAFFAR1KDM4EKDR | |
| SCHEMBL3280652 | 0.70 | PPARG (0.53) | PPARGPPARA | |
| SCHEMBL31180878 | 0.70 | PTPN1 (0.49) | PPARGPPARAFFAR1 | |
| SCHEMBL3279195 | 0.70 | FFAR1 (0.63) | PPARGPPARAFFAR1KDR | |
| SCHEMBL3278877 | 0.70 | PPARG (0.61) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152255-A1 | Organic Compounds | DAMON ROBERT EDSON | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152255-A1 | Organic Compounds | PPARG, FABP2, PPARA | PPARG 1/4885PPARA 3/4885FFAR1 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.