SCHEMBL3342391

SCHEMBL3342391

COC(=O)C1CC[C@H](NC(=O)OC(C)(C)C)C(NC(=O)c2cc3cc(Cl)ccc3[nH]2)C1

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 19/20 0.53
F2 P00734 1/20 0.50
PLAT P00750 1/20 0.50
EHMT2 Q96KQ7 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4270766 1.00 F10 (0.53) F10F2PLATEHMT2
SCHEMBL10476602 1.00 F10 (0.53) F10F2PLATEHMT2
SCHEMBL3342385 1.00 F10 (0.53) F10F2PLATEHMT2
SCHEMBL4087543 1.00 F10 (0.53) F10F2PLATEHMT2
SCHEMBL2712286 0.92 F10 (0.58) F10F2PLATEHMT2
SCHEMBL2711620 0.92 F10 (0.58) F10F2PLATEHMT2
SCHEMBL13379085 0.92 F10 (0.58) F10F2PLATEHMT2
SCHEMBL2711621 0.92 F10 (0.58) F10F2PLATEHMT2
SCHEMBL10476585 0.92 F10 (0.58) F10F2PLATEHMT2
SCHEMBL4361192 0.92 F10 (0.58) F10F2PLATEHMT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1577301-B1 Antithrombotic diaminocyclohexane derivatives DAIICHI SANKYO CO LTD (JP) 2012-09-12 EP disclosed
US-20100099660-A1 METHOD FOR TREATING THROMBOSIS OR EMBOLISM AND RELATED DISEASES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2010-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099660-A1 METHOD FOR TREATING THROMBOSIS OR EMBOLISM AND RELATED DISEASES F2, PLAT, MPL F10 152/4885F2 1/4885PLAT 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.