Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15307543 | 1.00 | EPHX1 (0.67) | EPHX1TSHRMEN1TP53CYP1A2 | |
| SCHEMBL2533818 | 1.00 | EPHX1 (0.67) | EPHX1TSHRMEN1TP53CYP1A2 | |
| SCHEMBL5089398 | 1.00 | EPHX1 (0.67) | EPHX1TSHRMEN1TP53CYP1A2 | |
| SCHEMBL6689012 | 1.00 | EPHX1 (0.67) | EPHX1TSHRMEN1TP53CYP1A2 | |
| SCHEMBL1692473 | 1.00 | EPHX1 (0.67) | EPHX1TSHRMEN1TP53CYP1A2 | |
| SCHEMBL4071198 | 1.00 | EPHX1 (0.67) | EPHX1TSHRMEN1TP53CYP1A2 | |
| SCHEMBL9458781 | 1.00 | EPHX1 (0.67) | EPHX1TSHRMEN1TP53CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL6580821 | 0.98 | EPHX1 (0.64) | EPHX1TSHRMEN1TP53CYP1A2 | |
| SCHEMBL5598408 | 0.86 | EPHX1 (0.67) | EPHX1TSHRMEN1TP53CYP1A2 | |
| SCHEMBL5598863 | 0.86 | EPHX1 (0.67) | EPHX1TSHRMEN1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601778-B1 | STEREOSELECTIVE CHEMOENZYMATIC PROCESS FOR PREPARING OPTICALLY ENRICHED PHENYLGLYCIDATES | COUNCIL SCIENT IND RES (IN) | 2008-07-02 | — | — | EP | claimed |
| EP-0821679-B1 | ASYMMETRIC EPOXIDES, THEIR SYNTHESIS AND USE | CHIROTECH TECHNOLOGY LTD (GB) | 2001-07-11 | — | — | EP | claimed |
| EP-0602740-B1 | Process for the enzymatic preparation of optically active transglycidic acid esters | DSM NV (NL) | 1999-02-24 | — | — | EP | claimed |
| US-5684168-A | β-phenylisoserine-(2R,3S), salts, preparation and use thereof | RHONE-POULENC RORER S.A. (FR) | 1997-11-04 | — | — | US | claimed |
| EP-0528607-B1 | Process for preparing optically active 3-phenylglycidic acid esters | TANABE SEIYAKU CO (JP) | 1997-04-23 | — | — | EP | claimed |
| EP-0447938-B1 | Process for preparing 2-halogeno-3-hydroxy-3-phenyl-propionic acid ester compounds | TANABE SEIYAKU CO (JP) | 1995-10-18 | — | — | EP | claimed |
| US-5407828-A | Hydrolysis; separation of non-hydrolyzed enantiomorph | DSM N.V. (NL) | 1995-04-18 | — | — | US | claimed |
| US-5378627-A | TREATING A TRANS-3-PHENYLGLYCIDIC ACID AND AN ALKANOL IN A SOLVENT WITH A HYDROLASE WHICH PREFERENTIALLY ESTERIFIES ONE ISOMER OF THE RACEMIC MIXTURE | TANABE SEIYAKU CO., LTD. (JP) | 1995-01-03 | — | — | US | claimed |
| EP-0602740-A1 | Process for the enzymatic preparation of optically active transglycidic acid esters | DSM N.V. (NL) | 1994-06-22 | — | — | EP | claimed |
| US-5204248-A | Enzymatic reduction of corresponding oxo derivative; intermediate for diltiazem | TANABE SEIYAKU CO., LTD. (JP) | 1993-04-20 | — | — | US | claimed |
| EP-0528607-A2 | Process for preparing optically active 3-phenylglycidic acid esters | TANABE SEIYAKU CO., LTD. (JP) | 1993-02-24 | — | — | EP | claimed |
| EP-0447938-A1 | Process for preparing 2-halogeno-3-hydroxy-3-phenyl-propionic acid ester compounds | TANABE SEIYAKU CO., LTD. (JP) | 1991-09-25 | — | — | EP | claimed |
| JP-5068588-A | — | — | None | — | — | JP | disclosed |
| JP-6335399-A | — | — | None | — | — | JP | disclosed |
| JP-8131189-A | — | — | None | — | — | JP | disclosed |
| EP-4065231-A1 | COVALENT RAS INHIBITORS AND USES THEREOF | Revolution Medicines, Inc. (US) | 2022-10-05 | — | — | EP | disclosed |
| EP-0489831-A1 | Substituted quinolines, their preparation and their use as lipoxygenase inhibitors and/or leukotriene antagonists | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 1992-06-17 | — | — | EP | disclosed |
| WO-1991013066-A2 | METHOD FOR PREPARING CIS-β-PHENYLGLYCIDIC-(2R,3R) ACID | RHONE-POULENC RORER S.A. (FR) | 1991-09-05 | — | — | WO | disclosed |
| WO-1991003466-A1 | SUBSTITUTED QUINOLINES | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LØVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB (DK) | 1991-03-21 | — | — | WO | disclosed |
| JP-H00568588-A | — | — | 0001-01-01 | — | — | JP | disclosed |