SCHEMBL334335

SCHEMBL334335

CCO[Si](CCS(=O)(O)=S)(OCC)OCC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL334570 0.86
SCHEMBL14090747 0.83 PTGS1 (0.33)
SCHEMBL28351321 0.78
SCHEMBL5484296 0.78
Thiosulfuric Acid SCHEMBL31613054 0.78 TP53 (0.34)
Thiosulfuric Acid SCHEMBL31613053 0.76 TP53 (0.37)
Sulfuric Acid SCHEMBL23456674 0.76 TP53 (0.34)
Thiosulfuric Acid SCHEMBL31613056 0.76
SCHEMBL991537 0.75 APP (0.38)
SCHEMBL15093629 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1341843-B2 MINERAL-FILLED ELASTOMER COMPOSITIONS MOMENTIVE PERFORMANCE MAT INC (US) 2016-03-23 EP claimed
US-8097743-B2 Process for manufacture of blocked mercaptosilane coupling agents MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-01-17 US claimed
EP-2213477-A1 Rubber composition and tire The Goodyear Tire & Rubber Company (US) 2010-08-04 EP claimed
US-20100190885-A1 TIRE WITH RUBBER COMPONENT CONTAINING SILICA AND USE OF COMBINATION OF BLOCKED AND UNBLOCKED ALKOXYORGANOMERCAPTOSILANE COUPLING AGENTS HUA KUO-CHIH 2010-07-29 US claimed
EP-1491545-B1 Method of preparing a composite of hydrophobated amorphous silica employing blocked mercaptoalkoxysilanes GOODYEAR TIRE & RUBBER (US) 2009-01-14 EP claimed
EP-0958298-B2 BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS MOMENTIVE PERFORMANCE MAT INC (US) 2008-10-22 EP claimed
US-7301042-B2 Blocked mercaptosilane hydrolyzates as coupling agents for mineral-filled elastomer compositions MOMENTIVE PERFORMANCE MATERIALS INC. 2007-11-27 US claimed
US-20070093612-A1 Composition, cured article, and associated method GENERAL ELECTRIC COMPANY (US) 2007-04-26 US claimed
EP-1341843-B1 MINERAL-FILLED ELASTOMER COMPOSITIONS GEN ELECTRIC (US) 2007-01-17 EP claimed
US-7122590-B2 Silicon compounds such as 2-triethoxysilyl-1-ethylthioacetate, used as binders of rubbers such as butadiene-styrene copolymers, containing fillers GENERAL ELECTRIC COMPANY (US) 2006-10-17 US claimed
US-6635700-B2 Mixture of a latent mercaptosilane coupling agent and an additional mercaptan activator used to cure sulfur vulcanizable rubber CROMPTON CORPORATION 2003-10-21 US claimed
EP-1341843-A2 MINERAL-FILLED ELASTOMER COMPOSITIONS Crompton Corporation (US) 2003-09-10 EP claimed
EP-0958298-B1 BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS CROMPTON CORP (US) 2003-05-07 EP claimed
US-6528673-B2 Reacting a mercaptosilane and a monoacid anhydride corresponding to a thioester group present in the desired product, or reacting alkali salt of a mercaptosilane with an acid anhydride or acid halide or transesterification CROMPTON CORPORATION 2003-03-04 US claimed
US-20020115767-A1 Mineral-filled elastomer compositions MOMENTIVE PERFORMANCE MATERIALS INC. 2002-08-22 US claimed
US-6414061-B1 CURABLE MIXTURE CROMPTON CORPORATION 2002-07-02 US claimed
WO-2002048256-A2 MINERAL-FILLED ELASTOMER COMPOSITIONS CROMPTON CORPORATION (US) 2002-06-20 WO claimed
US-20020055646-A1 Reacting a mercaptosilane and a monoacid anhydride corresponding to a thioester group present in the desired product, or reacting alkali salt of a mercaptosilane with an acid anhydride or acid halide or transesterification WITCO CORPORATION 2002-05-09 US claimed
EP-0958298-A1 BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS WITCO CORPORATION (US) 1999-11-24 EP claimed
WO-1999009036-A1 BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS OSI SPECIALTIES, INC. (US) 1999-02-25 WO claimed