SCHEMBL334370

CC(C)C[C@@H](NC(=O)[C@H](N)CCCNC(=N)N)C(=O)N(C(=O)OCc1ccccc1)[C@H](CNC(=O)CCCCCc1ccccc1)C(C)C

nearest known ligand 0.46

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	NPY4R	P50391	17/20	0.46

▸	NPY1R	P25929	11/20	0.46

▸	NPY5R	Q15761	10/20	0.46

▸	NPY2R	P49146	7/20	0.46

▸	CAPN1	P07384	1/20	0.42

▸	CAPN2	P17655	1/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL335149	0.91	NPY4R (0.48)	NPY4RNPY1RNPY5RNPY2RCAPN1
SCHEMBL334718	0.87	NPY4R (0.51)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL334369	0.87	NPY4R (0.51)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL334650	0.86	NPY4R (0.50)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL335509	0.86	NPY4R (0.50)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL334017	0.85	NPY4R (0.46)	NPY4RNPY1RNPY5RNPY2RCAPN1
SCHEMBL334604	0.85	NPY4R (0.53)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL334081	0.85	NPY4R (0.53)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL334069	0.85	NPY4R (0.46)	NPY4RNPY1RNPY5RNPY2RCAPN1
SCHEMBL334372	0.85	NPY4R (0.46)	NPY4RNPY1RNPY5RNPY2RCAPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8097582-B2	Peptide derivatives useful as antimicrobial agents and for treating wounds	NEOBIOTICS AB (SE)	2012-01-17	—	—	US	claimed