Adenosine

Adenosine

SCHEMBL3343948

Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O.O=P([O-])([O-])OP(=O)([O-])OP(=O)([O-])[O-].O=P([O-])([O-])OP(=O)([O-])OP(=O)([O-])[O-].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2]

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3

The experimentally established mechanism targets of Adenosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA1 known ✓ P30542 3/20 0.75
ADORA3 known ✓ P0DMS8 1/20 0.75
ADORA2A known ✓ P29274 1/20 0.75
ADORA2B known ✓ P29275 1/20 0.75
SMN1; SMN2 Q16637 3/20 0.75
DPP4 P27487 1/20 0.75
MEN1 O00255 1/20 0.75
SLC28A1 O00337 1/20 0.75
MAP3K7 O43318 1/20 0.75
SLC28A2 O43868 1/20 0.75
GAPDH P04406 1/20 0.75
MAPK1 P28482 1/20 0.75
STAT6 P42226 1/20 0.75
PI4KA P42356 1/20 0.75
KMT2A Q03164 1/20 0.75
PI4K2B Q8TCG2 1/20 0.75
DOT1L Q8TEK3 1/20 0.75
SLC29A1 Q99808 1/20 0.75
PI4K2A Q9BTU6 1/20 0.75
SLC28A3 Q9HAS3 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenosine SCHEMBL3183004 0.99 ADORA1 (0.77) ADORA1SMN1; SMN2DPP4MEN1SLC28A1
Adenosine SCHEMBL2442774 0.99 ADORA1 (0.77) ADORA1SMN1; SMN2DPP4MEN1SLC28A1
Adenosine SCHEMBL3134331 0.98 ADORA1 (0.75) ADORA1SMN1; SMN2DPP4MEN1SLC28A1
Adenosine SCHEMBL7516483 0.98 ADORA1 (0.75) ADORA1SMN1; SMN2DPP4MEN1SLC28A1
Adenosine SCHEMBL926532 0.98 ADORA1 (0.75) ADORA1SMN1; SMN2DPP4MEN1SLC28A1
Adenosine SCHEMBL924728 0.98 ADORA1 (0.75) ADORA1SMN1; SMN2DPP4MEN1SLC28A1
Adenosine SCHEMBL3166848 0.98 ADORA1 (0.75) ADORA1SMN1; SMN2DPP4MEN1SLC28A1
Adenosine SCHEMBL925631 0.98 ADORA1 (0.75) ADORA1SMN1; SMN2DPP4MEN1SLC28A1
Adenosine SCHEMBL10396858 0.97 ADORA1 (0.74) ADORA1SMN1; SMN2DPP4MEN1SLC28A1
Adenosine SCHEMBL3332132 0.97 ADORA1 (0.74) ADORA1SMN1; SMN2DPP4MEN1SLC28A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120025982-A Rectal cancer organoid culture kit and culture method thereof 上海市浦东新区公利医院(第二军医大学附属公利医院) 2025-05-23 CN claimed
CN-113274538-B bFGF slow-release nano dressing with wound surface active repair function and preparation method and application thereof 中国科学院过程工程研究所 2022-09-06 CN claimed
CN-113274538-A bFGF slow-release nano dressing with wound surface active repair function and preparation method and application thereof 中国科学院过程工程研究所 2021-08-20 CN claimed
CN-101730470-A Acaricidal active ingredient combinations BAYER CROPSCIENCE AG 2010-06-09 CN claimed
CN-1100266-C Luciferase labelling method SECR DEFENCE (GB) 2003-01-29 CN claimed
EP-0778945-B1 LUCIFERASE LABELLING METHOD SECR DEFENCE (GB) 2001-10-04 EP claimed
US-5837465-A Luciferase labelling method THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND OF DEFENCE EVALUATION & RESEARCH AGENCY (GB) 1998-11-17 US claimed
CN-1161746-A Luciferase labelling method SECR DEFENCE (GB) 1997-10-08 CN claimed
EP-0778945-A2 LUCIFERASE LABELLING METHOD THE SECRETARY OF STATE FOR DEFENCE (GB) 1997-06-18 EP claimed
WO-1996007100-A2 LUCIFERASE LABELLING METHOD THE SECRETARY OF STATE FOR DEFENCE (GB) 1996-03-07 WO claimed
WO-2026102230-A2 INCREASED NITROGEN FIXATION USING BACTERIA WITH MODIFIED ELECTRON TRANSPORT GENES Bayer CropScience LLC (US) 2026-05-15 WO disclosed
EP-4618744-A1 INCREASED NITROGEN FIXATION USING BACTERIA WITH IMPROVED AMMONIA SECRETION Bayer CropScience LP (US) 2025-09-24 EP disclosed
WO-2025023638-A1 METHOD FOR PRODUCING AMMONIA USING QUANTUM DOT-BACTERIA HYBRID SYSTEM 한국과학기술원 2025-01-30 WO disclosed
WO-2024108099-A1 INCREASED NITROGEN FIXATION USING BACTERIA WITH IMPROVED AMMONIA SECRETION BAYER CROPSCIENCE LP (US) 2024-05-23 WO disclosed
CN-113274538-B bFGF slow-release nano dressing with wound surface active repair function and preparation method and application thereof 中国科学院过程工程研究所 2022-09-06 CN disclosed
EP-0586381-A1 IMPROVED BLOOD SUBSTITUTE Texas Tech University Health Sciences Center (US) 1994-03-16 EP disclosed
EP-0507870-A4 POLYHEMOGLOBIN STABILIZED BY PURINE DERIVATIVES AND GLUTATHIONE 1993-08-11 EP disclosed
EP-0507870-A1 POLYHEMOGLOBIN STABILIZED BY PURINE DERIVATIVES AND GLUTATHIONE. UNIV TEXAS TECH (US) 1992-10-14 EP disclosed
WO-1992013875-A1 IMPROVED BLOOD SUBSTITUTE TEXAS TECH UNIVERSITY (US) 1992-08-20 WO disclosed
WO-1991009615-A1 POLYHEMOGLOBIN STABILIZED BY PURINE DERIVATIVES AND GLUTATHIONE TEXAS TECH UNIVERSITY (US) 1991-07-11 WO disclosed