Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 15/20 | 0.68 |
| ▸ | PPARG | P37231 | 13/20 | 0.68 |
| ▸ | PPARA | Q07869 | 12/20 | 0.68 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10220936 | 1.00 | PPARD (0.68) | PPARDPPARGPPARACSNK1DAKR1B1 | |
| SCHEMBL334314 | 0.91 | PPARD (0.57) | PPARDPPARGPPARACSNK1D | |
| SCHEMBL10220932 | 0.91 | PPARD (0.57) | PPARDPPARGPPARACSNK1D | |
| SCHEMBL10220944 | 0.90 | PPARD (0.83) | PPARDPPARGPPARAAKR1B1 | |
| SCHEMBL10220445 | 0.90 | PPARD (0.85) | PPARDPPARGPPARACSNK1D | |
| SCHEMBL10220403 | 0.90 | PPARD (0.85) | PPARDPPARGPPARACSNK1D | |
| SCHEMBL10220433 | 0.90 | PPARD (0.85) | PPARDPPARGPPARACSNK1D | |
| SCHEMBL10220395 | 0.87 | PPARD (0.66) | PPARDPPARGPPARACSNK1D | |
| SCHEMBL10220400 | 0.85 | PPARD (0.67) | PPARDPPARGPPARACSNK1D | |
| SCHEMBL10220409 | 0.84 | PPARD (0.83) | PPARDPPARGPPARACSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097610-B2 | Derivative having PPAR agonistic activity | SHIONOGI & CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-20090286974-A1 | Derivative having ppar agonistic activity | SHIONOGI & CO., LTD. (JP) | 2009-11-19 | — | — | US | disclosed |
| EP-1939189-A1 | DERIVATIVE HAVING PPAR AGONISTIC ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2008-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286974-A1 | Derivative having ppar agonistic activity | PPARD, PPARA, PPARG | PPARD 1/4885PPARG 3/4885PPARA 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.