Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2301521 | 0.84 | ADORA1 (1.00) | ADORA2AADORA1 | |
| SCHEMBL3306497 | 0.83 | ADORA2A (0.82) | ADORA2AADORA1 | |
| SCHEMBL3350962 | 0.82 | ADORA2A (0.74) | ADORA2AADORA1 | |
| SCHEMBL13389826 | 0.81 | ADORA2A (0.71) | ADORA2AADORA1 | |
| SCHEMBL3304444 | 0.81 | ADORA2A (0.71) | ADORA2AADORA1 | |
| SCHEMBL2305928 | 0.78 | ADORA1 (1.00) | ADORA2AADORA1 | |
| SCHEMBL3300813 | 0.78 | ADORA2A (0.67) | ADORA2AADORA1 | |
| SCHEMBL3295339 | 0.78 | ADORA2A (0.72) | ADORA2AADORA1 | |
| SCHEMBL2304290 | 0.78 | ADORA2A (1.00) | ADORA2AADORA1 | |
| SCHEMBL2301454 | 0.77 | ADORA1 (1.00) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010045016-A1 | HETEROCYCLYL AND CYCLOALKYL SUBSTITUTED THIENO [2,3-D] PYRIMIDINE AND THEIR USE AS ADENOSINE A2A RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2010-04-22 | — | — | WO | disclosed |