⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5559610 | 0.51 | — | — | |
| SCHEMBL976327 | 0.50 | — | — | |
| Pyrazine SCHEMBL1226089 | 0.26 | TSHR (0.50) | — | |
| SCHEMBL8512657 | 0.26 | HSP90AA1 (0.36) | — | |
| Pyrazine SCHEMBL5179 | 0.26 | — | — | |
| Methane SCHEMBL23044967 | 0.21 | — | — | |
| SCHEMBL8636316 | 0.21 | — | — | |
| SCHEMBL6559802 | 0.21 | — | — | |
| SCHEMBL2968919 | 0.21 | — | — | |
| SCHEMBL1532368 | 0.21 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7871982-B2 | Lincomycin derivatives and antimicrobial agents comprising the same as active ingredient | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-01-18 | — | — | US | claimed |
| US-20090156512-A1 | potent activity against resistant pneumococci | MEIJI SEIKA KAISHA, LTD. (JP) | 2009-06-18 | — | — | US | claimed |
| EP-1970377-A1 | LINCOMYCIN DERIVATIVE AND ANTIBACTERIAL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2008-09-17 | — | — | EP | claimed |
| US-20070167423-A1 | QUINOLINE AND QUINAZOLINE DERIVATIVES HAVING AFFINITY FOR 5HT1-TYPE RECEPTORS | GLAXO GROUP LIMITED | 2007-07-19 | — | — | US | claimed |
| EP-0774466-A1 | NOVEL CEPHEM DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-05-21 | — | — | EP | claimed |
| US-20240174710-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS | WAVE LIFE SCIENCES LTD. (SG) | 2024-05-30 | — | — | US | disclosed |
| US-20240051966-A1 | CD16A BINDING AGENTS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. | 2024-02-15 | — | — | US | disclosed |
| US-11873316-B2 | Compositions and methods for phosphoramidite and oligonucleotide synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-16 | — | — | US | disclosed |
| US-11834482-B2 | Agents modulating beta-catenin functions and methods thereof | FOG PHARMACEUTICALS, INC. (US) | 2023-12-05 | — | — | US | disclosed |
| US-20230348524-A1 | TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-02 | — | — | US | disclosed |
| US-11739325-B2 | Oligonucleotide compositions and methods thereof | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-29 | — | — | US | disclosed |
| US-11718638-B2 | Compounds, compositions and methods for synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-08 | — | — | US | disclosed |
| WO-2006133946-A1 | AZAB I CYCLO [3 . 1 . 0] HEXANE DERIVATIVES AS DOPAMIN D3 RECEPTOR MODULATORS | GLAXO GROUP LIMITED (GB) | 2006-12-21 | — | — | WO | disclosed |
| US-20060229312-A1 | Quinoline and quinazoline derivatives having affinity for 5ht1-type receptors | GLAXO GROUP LIMITED (GB) | 2006-10-12 | — | — | US | disclosed |
| WO-2006002928-A1 | COMPOUNDS HAVING AFFINITY FOR THE DOPAMINE D3 RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2006-01-12 | — | — | WO | disclosed |
| WO-2005040095-A1 | INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | ASTRAZENECA AB (SE) | 2005-05-06 | — | — | WO | disclosed |
| WO-2001053305-A1 | PROCESSES FOR THE PREPARATION OF CARBAPENEM DERIVATIVES | MEIJI SEIKA KAISHA, LTD. (JP) | 2001-07-26 | — | — | WO | disclosed |
| EP-0774466-A4 | NOVEL CEPHEM DERIVATIVES | MEIJI SEIKA CO (JP) | 1998-09-02 | — | — | EP | disclosed |
| EP-0774466-A1 | NOVEL CEPHEM DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996037499-A1 | NOVEL CEPHEM DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1996-11-28 | — | — | WO | disclosed |