SCHEMBL3345848

SCHEMBL3345848

COc1ccc(C(Br)(Br)Br)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.61
CA2 P00918 2/20 0.61
CA7 P43166 2/20 0.61
CA9 Q16790 2/20 0.61
CA12 O43570 1/20 0.61
CA14 Q9ULX7 1/20 0.61
ACHE P22303 1/20 0.50
TDP1 Q9NUW8 5/20 0.48
MAPK1 P28482 4/20 0.48
ALDH1A1 P00352 4/20 0.46
MAPT P10636 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
RECQL P46063 2/20 0.46
KDM4E B2RXH2 1/20 0.46
NPC1 O15118 1/20 0.46
GAA P10253 1/20 0.46
THRB P10828 1/20 0.46
RAB9A P51151 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
CYP3A4 P08684 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL678596 0.83 CA1 (0.61) CA1CA2CA7CA9CA12
SCHEMBL7030329 0.83 CA1 (0.61) CA1CA2CA7CA9CA12
SCHEMBL12227837 0.80 CA1 (0.65) CA1CA2CA7CA9CA12
SCHEMBL30676990 0.80 CA1 (0.65) CA1CA2CA7CA9CA12
SCHEMBL8237312 0.79 CA1 (0.55) CA1CA2CA7CA9CA12
1,4-Dimethoxybenzene SCHEMBL21802643 0.78 CA1 (1.00) CA1CA2CA7CA9CA12
1,4-Dimethoxybenzene SCHEMBL8489 0.78 CA1 (1.00) CA1CA2CA7CA9CA12
SCHEMBL10112753 0.78 CA1 (0.61) CA1CA2CA7CA9CA12
SCHEMBL1538395 0.78 CA1 (0.61) CA1CA2CA7CA9CA12
SCHEMBL3098811 0.78 CA1 (0.61) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010046384-A1 A LITHOGRAPHIC PRINTING PLATE AGFA GRAPHICS NV (BE) 2010-04-29 WO disclosed
US-4220765-A Process for the preparation of 4,6-dihalogeno-triazines BAYER AKTIENGESELLSCHAFT (DE) 1980-09-02 US disclosed
EP-0002493-B1 PROCESS FOR THE PREPARATION OF 4,6-DIHALOGENO-1,3,5-TRIAZINES BAYER AG (DE) 1980-07-23 EP disclosed
EP-0002493-A1 Process for the preparation of 4,6-dihalogeno-1,3,5-triazines BAYER AG (DE) 1979-06-27 EP disclosed