Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CETP | P11597 | 3/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14556164 | 0.85 | TSHR (0.55) | TSHRCETPELANESRCFOLH1 | |
| SCHEMBL206609 | 0.84 | TSHR (0.68) | TSHRCETPELANESRCALDH1A1 | |
| SCHEMBL11276825 | 0.82 | TSHR (0.52) | TSHRCETPELANESRCPDPK1 | |
| SCHEMBL3341018 | 0.82 | TSHR (0.52) | TSHRCETPELANESRCPDPK1 | |
| SCHEMBL743706 | 0.79 | TSHR (0.57) | TSHRCETPELANE | |
| SCHEMBL2980165 | 0.79 | TSHR (0.57) | TSHRCETPELANE | |
| SCHEMBL5379773 | 0.79 | TSHR (0.61) | TSHRCETPELANESRCALDH1A1 | |
| SCHEMBL18422870 | 0.78 | TSHR (0.47) | TSHRCETPELANESRCMAOB | |
| SCHEMBL22905969 | 0.77 | TSHR (0.50) | TSHRCETPELANESRCFOLH1 | |
| SCHEMBL991032 | 0.77 | TSHR (0.59) | TSHRCETPELANESRCFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039474-A1 | PRODRUGS OF OXAZOLIDINONE CETP INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2010-04-08 | — | — | WO | disclosed |