Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3318526 | 0.87 | IGF1R (0.64) | IGF1RKCNH2 | |
| SCHEMBL3313499 | 0.84 | IGF1R (0.76) | IGF1RKCNH2 | |
| SCHEMBL3311216 | 0.83 | IGF1R (0.67) | IGF1RKCNH2 | |
| SCHEMBL3315964 | 0.83 | IGF1R (0.68) | IGF1RKCNH2 | |
| SCHEMBL3311801 | 0.83 | IGF1R (0.66) | IGF1RKCNH2 | |
| SCHEMBL3314225 | 0.82 | IGF1R (0.64) | IGF1RKCNH2 | |
| SCHEMBL3309415 | 0.81 | IGF1R (0.64) | IGF1RKCNH2 | |
| SCHEMBL3314782 | 0.81 | IGF1R (0.62) | IGF1RKCNH2 | |
| SCHEMBL3316240 | 0.81 | IGF1R (0.61) | IGF1RKCNH2 | |
| SCHEMBL3317767 | 0.80 | IGF1R (0.80) | IGF1RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010049731-A1 | PYRAZOLO- AND IMIDAZOPYRIDINYLPYRIMIDINEAMINES AS IGF-1R TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2010-05-06 | — | — | WO | disclosed |