Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 11/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25365985 | 1.00 | ADORA1 (0.55) | ADORA1ADORA2AADORA2BKDM4EALDH1A1 | |
| SCHEMBL13929770 | 0.89 | KDM4E (0.52) | ADORA1ADORA2AADORA2BKDM4EALDH1A1 | |
| SCHEMBL31378287 | 0.86 | ADORA1 (0.49) | ADORA1ADORA2AADORA2BKDM4EALDH1A1 | |
| SCHEMBL1931221 | 0.85 | ADORA1 (0.50) | ADORA1ADORA2AADORA2BKDM4EALDH1A1 | |
| SCHEMBL31409451 | 0.84 | ADORA1 (0.49) | ADORA1ADORA2AADORA2BKDM4EALDH1A1 | |
| SCHEMBL3338306 | 0.84 | ADORA1 (0.60) | ADORA1ADORA2AADORA2BKDM4EALDH1A1 | |
| SCHEMBL245940 | 0.83 | PRF1 (0.58) | ADORA1ADORA2AADORA2BKDM4EALDH1A1 | |
| SCHEMBL30511861 | 0.83 | PRF1 (0.58) | ADORA1ADORA2AADORA2BKDM4EALDH1A1 | |
| SCHEMBL1931610 | 0.82 | ADORA1 (0.47) | ADORA1ADORA2AADORA2BKDM4EALDH1A1 | |
| SCHEMBL3598502 | 0.82 | ADORA1 (0.47) | ADORA1ADORA2AADORA2BKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012000945-A1 | SUBSTITUTED DICYANOPYRIDINES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-05 | — | — | WO | disclosed |