Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 14/20 | 0.70 |
| ▸ | ADORA1 | P30542 | 10/20 | 0.58 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3303145 | 0.82 | ADORA2A (1.00) | ADORA2AADORA1 | |
| SCHEMBL3296743 | 0.81 | ADORA2A (0.64) | ADORA2AADORA1KDM4EMEN1ALDH1A1 | |
| SCHEMBL2306306 | 0.79 | ADORA2A (0.60) | ADORA2AADORA1PLAU | |
| SCHEMBL13389229 | 0.79 | ADORA2A (0.55) | ADORA2AADORA1KDM4EMEN1ALDH1A1 | |
| SCHEMBL3296688 | 0.79 | ADORA2A (0.54) | ADORA2AADORA1HSP90AB1MEN1KMT2A | |
| SCHEMBL2303619 | 0.79 | ADORA2A (0.60) | ADORA2AADORA1 | |
| SCHEMBL3300662 | 0.78 | ADORA2A (0.54) | ADORA2AADORA1KMT2A | |
| Hydrochloric Acid SCHEMBL3302026 | 0.78 | ADORA2A (0.54) | ADORA2AADORA1KDM4EMEN1ALDH1A1 | |
| SCHEMBL27856975 | 0.77 | ADORA2A (0.71) | ADORA2AADORA1 | |
| SCHEMBL13389260 | 0.77 | ADORA2A (0.59) | ADORA2AADORA1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010045008-A1 | AMIDES OF THIENO[2,3-d]PYRIMIDINE AND THEIR USE AS ADENOSINE A2a RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2010-04-22 | — | — | WO | disclosed |