Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 12/20 | 0.64 |
| ▸ | MAOB | P27338 | 12/20 | 0.64 |
| ▸ | MAOA | P21397 | 9/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3349212 | 1.00 | KDM1A (0.64) | KDM1AMAOBMAOALMNASMN1; SMN2 | |
| SCHEMBL2339013 | 0.89 | KDM1A (0.58) | KDM1AMAOBMAOALMNASMN1; SMN2 | |
| SCHEMBL15224139 | 0.84 | KDM1A (0.59) | KDM1AMAOBMAOAPOLB | |
| SCHEMBL15224140 | 0.84 | KDM1A (0.59) | KDM1AMAOBMAOAPOLB | |
| SCHEMBL12242302 | 0.78 | KDM1A (1.00) | KDM1AMAOBMAOA | |
| SCHEMBL1287581 | 0.78 | KDM1A (1.00) | KDM1AMAOBMAOA | |
| SCHEMBL20260492 | 0.78 | KDM1A (1.00) | KDM1AMAOBMAOA | |
| SCHEMBL1287584 | 0.78 | KDM1A (1.00) | KDM1AMAOBMAOA | |
| SCHEMBL2337981 | 0.78 | KDM1A (1.00) | KDM1AMAOBMAOA | |
| Hydrochloric Acid SCHEMBL29765414 | 0.77 | KDM1A (0.98) | KDM1AMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361242-B1 | OXIDASE INHIBITORS AND THEIR USE | ORYZON GENOMICS SA (ES) | 2018-08-01 | — | — | EP | disclosed |
| WO-2010043721-A1 | OXIDASE INHIBITORS AND THEIR USE | ORYZON GENOMICS, S.A. (ES) | 2010-04-22 | — | — | WO | disclosed |