Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL5471260 | 0.95 | TSHR (0.54) | — | |
| Bicarbonate SCHEMBL28153573 | 0.95 | — | — | |
| Bicarbonate SCHEMBL28267422 | 0.95 | — | — | |
| Methylene Chloride SCHEMBL28160039 | 0.84 | — | — | |
| 1,2-Dichloroethane SCHEMBL2239695 | 0.84 | — | — | |
| Methylene Chloride SCHEMBL7847615 | 0.84 | TSHR (0.54) | — | |
| Isobutane SCHEMBL9025773 | 0.83 | TSHR (0.44) | — | |
| Bicarbonate SCHEMBL29569190 | 0.82 | — | — | |
| Methylene Chloride SCHEMBL28158615 | 0.82 | — | — | |
| Bicarbonate SCHEMBL9303939 | 0.80 | FFAR3 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117229692-A | Water-based epoxy resin spraying agent and preparation method and application thereof | 智仑超纯环氧树脂(西安)有限公司 | 2023-12-15 | — | — | CN | claimed |
| CN-115638542-A | Sheet generator system and dredging method | 聊城鲁西聚碳酸酯有限公司 | 2023-01-24 | — | — | CN | claimed |
| CN-217887031-U | Polycarbonate methylene dichloride recovery system | 聊城鲁西聚碳酸酯有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-104974210-B | A kind of preparation method of 17,21 pairs of hydroxy steroid derivatives | 天津金耀集团有限公司 | 2018-01-23 | — | — | CN | claimed |
| CN-104974209-B | A kind of synthetic method of 17,21 pairs of hydroxy steroid derivatives | 天津金耀集团有限公司 | 2018-01-19 | — | — | CN | claimed |
| US-4408040-A | Slurry granulation-steam stripping process for solvent removal | GENERAL ELECTRIC COMPANY (US) | 1983-10-04 | — | — | US | claimed |
| JP-8269187-A | — | — | None | — | — | JP | disclosed |
| CN-116217268-B | Polycarbonate transparent ceramic composite material and preparation method thereof | 松山湖材料实验室 | 2024-01-19 | — | — | CN | disclosed |
| CN-114369287-B | Laser foaming auxiliary agent composition and preparation method and application thereof | 万华化学集团股份有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-219517821-U | Double-blade evaporator for polycarbonate powder production | 上海芮澜工程科技有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-116217268-A | Polycarbonate transparent ceramic composite material and preparation method thereof | 松山湖材料实验室 | 2023-06-06 | — | — | CN | disclosed |
| CN-115638542-A | Sheet generator system and dredging method | 聊城鲁西聚碳酸酯有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-217887031-U | Polycarbonate methylene dichloride recovery system | 聊城鲁西聚碳酸酯有限公司 | 2022-11-25 | — | — | CN | disclosed |
| EP-0637601-A1 | Polymer granules and process for preparing the same | IDEMITSU PETROCHEMICAL CO. LTD. (JP) | 1995-02-08 | — | — | EP | disclosed |
| WO-1991000858-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS | SCHERING CORPORATION (US) | 1991-01-24 | — | — | WO | disclosed |
| EP-0002327-B1 | PHARMACOLOGICALLY ACTIVE 6-LOWER ALKYL-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINES, METHOD OF PREPARING THEM AND INTERMEDIATES | SMITHKLINE BECKMAN CORPORATION (US) | 1982-08-04 | — | — | EP | disclosed |
| US-4342686-A | Intermediates for preparing 6-lower alkyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines | SMITHKLINE CORPORATION (US) | 1982-08-03 | — | — | US | disclosed |
| US-4318773-A | Process for the concentration of solutions with simultaneous setting | BAYER AKTIENGESELLSCHAFT (DE) | 1982-03-09 | — | — | US | disclosed |
| US-4265889-A | DOPAMINERGIC, HYPOTENSIVE | SMITHKLINE CORPORATION (US) | 1981-05-05 | — | — | US | disclosed |
| EP-0002327-A1 | Pharmacologically active 6-lower alkyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines, method of preparing them and intermediates | SMITHKLINE BECKMAN CORPORATION (US) | 1979-06-13 | — | — | EP | disclosed |