Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.70 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.62 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.60 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.58 |
| ▸ | TUBB | P07437 | 1/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.58 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.58 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.58 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.58 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.58 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.58 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.58 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.58 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.58 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.58 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15930268 | 1.00 | HTT (0.72) | HTTHPGDHSP90AA1CYP2A6IMPDH2 | |
| SCHEMBL2189137 | 0.84 | HTT (1.00) | HTTHPGDHSP90AA1CYP2A6IMPDH2 | |
| SCHEMBL1643903 | 0.84 | HTT (0.68) | HTTHPGDHSP90AA1CYP2A6IMPDH2 | |
| SCHEMBL31355128 | 0.84 | HTT (1.00) | HTTHPGDHSP90AA1CYP2A6IMPDH2 | |
| SCHEMBL29786168 | 0.84 | HTT (0.68) | HTTHPGDHSP90AA1CYP2A6IMPDH2 | |
| SCHEMBL1643902 | 0.84 | HTT (0.68) | HTTHPGDHSP90AA1CYP2A6IMPDH2 | |
| SCHEMBL13622497 | 0.84 | HTT (0.68) | HTTHPGDHSP90AA1CYP2A6IMPDH2 | |
| SCHEMBL5167169 | 0.84 | HTT (1.00) | HTTHPGDHSP90AA1CYP2A6IMPDH2 | |
| SCHEMBL2189141 | 0.84 | HTT (1.00) | HTTHPGDHSP90AA1CYP2A6IMPDH2 | |
| SCHEMBL15928030 | 0.84 | HTT (0.54) | HTTHPGDHSP90AA1CYP2A6IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009104198-A2 | METAL CONJUGATES OF INDOLE 3- ALDEHYDE AZINE AND ITS DERIVATIVES AND USES THEREOF | VLIFE SCIENCES TECHNOLOGIES PVT. LTD. (IN) | 2009-08-27 | — | — | WO | claimed |
| WO-2009104198-A3 | METAL CONJUGATES OF INDOLE 3-ALDEHYDE AZINE AND ITS DERIVATIVES AND USES THEREOF | VLIFE SCIENCES TECHNOLOGIES PVT. LTD. (IN) | 2010-05-06 | — | — | WO | disclosed |
| WO-2009104198-A3 | METAL CONJUGATES OF INDOLE 3-ALDEHYDE AZINE AND ITS DERIVATIVES AND USES THEREOF | VLIFE SCIENCES TECHNOLOGIES PVT. LTD. (IN) | 2010-05-06 | — | — | WO | disclosed |
| WO-2009104198-A2 | METAL CONJUGATES OF INDOLE 3- ALDEHYDE AZINE AND ITS DERIVATIVES AND USES THEREOF | VLIFE SCIENCES TECHNOLOGIES PVT. LTD. (IN) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009104198-A2 | METAL CONJUGATES OF INDOLE 3- ALDEHYDE AZINE AND ITS DERIVATIVES AND USES THEREOF | VLIFE SCIENCES TECHNOLOGIES PVT. LTD. (IN) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009104198-A2 | METAL CONJUGATES OF INDOLE 3- ALDEHYDE AZINE AND ITS DERIVATIVES AND USES THEREOF | VLIFE SCIENCES TECHNOLOGIES PVT. LTD. (IN) | 2009-08-27 | — | — | WO | disclosed |