⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butadiene Epoxide SCHEMBL39877 | 1.00 | — | — | |
| Butadiene Epoxide SCHEMBL10496505 | 0.96 | — | — | |
| SCHEMBL1559778 | 0.96 | TDP1 (0.93) | — | |
| SCHEMBL1862726 | 0.78 | — | — | |
| SCHEMBL13822490 | 0.76 | — | — | |
| SCHEMBL5609192 | 0.76 | — | — | |
| Butadiene Epoxide SCHEMBL6067380 | 0.75 | TDP1 (0.56) | — | |
| SCHEMBL13838050 | 0.75 | TDP1 (0.56) | — | |
| SCHEMBL5087079 | 0.74 | TDP1 (0.57) | — | |
| SCHEMBL7697518 | 0.74 | TDP1 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118472210-A | Preparation method of silicon-carbon-coated anode material | 常州硅源新能材料有限公司 | 2024-08-09 | — | — | CN | claimed |
| US-12091425-B2 | Compounds that inhibit MCL-1 protein | AMGEN INC. (US) | 2024-09-17 | — | — | US | disclosed |
| CN-118472210-A | Preparation method of silicon-carbon-coated anode material | 常州硅源新能材料有限公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-112979705-B | Nucleotide analogue compound and salt, preparation method and pharmaceutical application thereof | 华创合成制药股份有限公司 | 2024-01-26 | — | — | CN | disclosed |
| US-20230052348-A1 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN | AMGEN INC. (US) | 2023-02-16 | — | — | US | disclosed |
| US-20220380309-A1 | CHOLINE METABOLISM INHIBITORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2022-12-01 | — | — | US | disclosed |
| US-11306107-B2 | Compounds that inhibit MCL-1 protein | AMGEN INC. (US) | 2022-04-19 | — | — | US | disclosed |
| US-20210230189-A1 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN | AMGEN INC. (US) | 2021-07-29 | — | — | US | disclosed |
| CN-112979705-A | Nucleotide analogue compound and salt thereof, preparation method and pharmaceutical application thereof | 华创合成制药股份有限公司 | 2021-06-18 | — | — | CN | disclosed |
| WO-2020117942-A1 | CHOLINE METABOLISM INHIBITORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-06-11 | — | — | WO | disclosed |
| US-20140206829-A1 | ISOSELECTIVE POLYMERIZATION OF EPOXIDES | CORNELL UNIVERSITY (US) | 2014-07-24 | — | — | US | disclosed |
| US-8710283-B2 | Isoselective polymerization of epoxides | CORNELL UNIVERSITY (US) | 2014-04-29 | — | — | US | disclosed |
| US-20130079491-A1 | ISOSELECTIVE POLYMERIZATION OF EPOXIDES | CORNELL UNIVERSITY (US) | 2013-03-28 | — | — | US | disclosed |
| US-8097708-B2 | 10a-Azalide compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| EP-2195305-A2 | ISOSELECTIVE POLYMERIZATION OF EPOXIDES | Cornell Research Foundation, Inc. (US) | 2010-06-16 | — | — | EP | disclosed |
| US-20100144969-A1 | ISOSELECTIVE POLYMERIZATION OF EPOXIDES | CORNELL UNIVERSITY (US) | 2010-06-10 | — | — | US | disclosed |
| EP-2175495-A1 | Sealed device | Fujifilm Corporation (JP) | 2010-04-14 | — | — | EP | disclosed |
| US-20090281292-A1 | 10a-Azalide Compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2009-11-12 | — | — | US | disclosed |
| WO-2009026261-A2 | ISOSELECTIVE POLYMERIZATION OF EPOXIDES | CORNELL RESEARCH FOUNDATION, INC. (US) | 2009-02-26 | — | — | WO | disclosed |
| EP-1985620-A1 | 10a-AZALIDE COMPOUND | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2008-10-29 | — | — | EP | disclosed |