SCHEMBL3350436

SCHEMBL3350436

O=C([C@H](O)[C@H](O)[C@H](O)CO)P(=O)(O)O

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.46
LMNA P02545 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
USP2 O75604 1/20 0.39
SLCO1B1 Q9Y6L6 1/20 0.39
PGD P52209 2/20 0.32
KDM4E B2RXH2 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL360335 0.93 PDE4A (0.56) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL28165325 0.93 PDE4A (0.56) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL6282106 0.93 PDE4A (0.56) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL27496778 0.91 PDE4A (0.54) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL9854945 0.80 CA12 (0.31) PGD
SCHEMBL526989 0.78 PDE4A (0.39) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL9387950 0.78
Phosphoric Acid SCHEMBL27669432 0.77 PDE4A (0.71) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL710524 0.77 USP2 (0.59) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL27637592 0.77 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0994715-A4 DIFLUORONUCLEOSIDE PHOSPHONIC ACIDS AND DERIVATIVES THEREOF LILLY CO ELI (US) 2001-08-08 EP claimed
EP-0994715-A1 DIFLUORONUCLEOSIDE PHOSPHONIC ACIDS AND DERIVATIVES THEREOF ELI LILLY AND COMPANY (US) 2000-04-26 EP claimed
WO-1998042351-A1 DIFLUORONUCLEOSIDE PHOSPHONIC ACIDS AND DERIVATIVES THEREOF ELI LILLY AND COMPANY (US) 1998-10-01 WO claimed
EP-0170257-B1 PROCESS FOR PRODUCING L-TRYPTOPHAN AJINOMOTO CO., INC. (JP) 1992-04-15 EP claimed
US-4885245-A CONTACTING GENETICALLY ENGINEERED CORYNEFORM BACTERIUM WITH APPROPRIATE RAW MATERIALS AJINOMOTO CO., INC. (JP) 1989-12-05 US claimed
EP-0170257-A2 Process for producing l-tryptophan AJINOMOTO CO., INC. (JP) 1986-02-05 EP claimed
CN-118562842-A Method for constructing high-efficiency biosynthesis hypoxanthine escherichia coli platform strain and synthesizing derivative thereof and application 北京化工大学 2024-08-30 CN disclosed
WO-2010018221-A1 NOVEL, ULTRA-SENSITIVE, AND QUICK METHOD FOR MEASURING THE LEVEL OF FRESHNESS OF ANIMAL MEAT BY ELECTROLUMINESCENCE NOVOCIB (FR) 2010-02-18 WO disclosed
EP-0994715-A4 DIFLUORONUCLEOSIDE PHOSPHONIC ACIDS AND DERIVATIVES THEREOF LILLY CO ELI (US) 2001-08-08 EP disclosed
EP-0994715-A1 DIFLUORONUCLEOSIDE PHOSPHONIC ACIDS AND DERIVATIVES THEREOF ELI LILLY AND COMPANY (US) 2000-04-26 EP disclosed
WO-1998042351-A1 DIFLUORONUCLEOSIDE PHOSPHONIC ACIDS AND DERIVATIVES THEREOF ELI LILLY AND COMPANY (US) 1998-10-01 WO disclosed
EP-0170257-B1 PROCESS FOR PRODUCING L-TRYPTOPHAN AJINOMOTO CO., INC. (JP) 1992-04-15 EP disclosed
US-4885245-A CONTACTING GENETICALLY ENGINEERED CORYNEFORM BACTERIUM WITH APPROPRIATE RAW MATERIALS AJINOMOTO CO., INC. (JP) 1989-12-05 US disclosed
EP-0170257-A2 Process for producing l-tryptophan AJINOMOTO CO., INC. (JP) 1986-02-05 EP disclosed