Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13182675 | 1.00 | NPC1 (0.41) | NPC1MAPTTDP1CYP1A2KMT2A | |
| SCHEMBL2366797 | 0.71 | NPC1 (0.41) | NPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL11541914 | 0.71 | HSD17B10 (0.46) | MAPTTDP1CYP1A2KMT2AMEN1 | |
| SCHEMBL12681500 | 0.68 | CYP1A2 (0.50) | NPC1MAPTTDP1CYP1A2KMT2A | |
| SCHEMBL13182733 | 0.67 | MAPT (0.38) | MAPTTDP1CYP1A2KMT2AHSD17B10 | |
| SCHEMBL3348537 | 0.67 | MAPT (0.38) | MAPTTDP1CYP1A2KMT2AHSD17B10 | |
| SCHEMBL11376213 | 0.65 | CA1 (0.41) | MAPTTDP1CYP1A2KMT2AHSD17B10 | |
| SCHEMBL7076313 | 0.65 | KDM4E (0.42) | MAPTTDP1CYP1A2KMT2AMEN1 | |
| SCHEMBL13261204 | 0.65 | MAPT (0.49) | MAPTTDP1KMT2AMEN1L3MBTL1 | |
| SCHEMBL9066864 | 0.64 | KMT2A (0.35) | MAPTTDP1CYP1A2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010106071-A1 | N-HYDROXY-L-METHYL-LH-PYRAZOLE-4-CARBOXAMIDE DERIVATIVES AND THEIR USE AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-09-23 | — | — | WO | disclosed |