Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 18/20 | 0.75 |
| ▸ | ADORA1 | P30542 | 17/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3309309 | 0.86 | ADORA2A (1.00) | ADORA2AADORA1ADORA3 | |
| SCHEMBL3300813 | 0.82 | ADORA2A (0.67) | ADORA2AADORA1 | |
| SCHEMBL3303429 | 0.81 | ADORA2A (0.64) | ADORA2AADORA1ADORA3 | |
| SCHEMBL3297795 | 0.81 | ADORA2A (0.65) | ADORA2AADORA1ADORA3 | |
| SCHEMBL3304836 | 0.80 | ADORA2A (0.58) | ADORA2AADORA1ADORA3 | |
| SCHEMBL3300340 | 0.80 | ADORA2A (0.60) | ADORA2AADORA1ADORA3 | |
| SCHEMBL3301866 | 0.80 | ADORA2A (0.58) | ADORA2AADORA1ADORA3 | |
| SCHEMBL3300645 | 0.80 | ADORA2A (0.68) | ADORA2AADORA1ADORA3 | |
| SCHEMBL13389224 | 0.80 | ADORA2A (0.68) | ADORA2AADORA1ADORA3 | |
| SCHEMBL3295339 | 0.79 | ADORA2A (0.72) | ADORA2AADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010045008-A1 | AMIDES OF THIENO[2,3-d]PYRIMIDINE AND THEIR USE AS ADENOSINE A2a RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2010-04-22 | — | — | WO | disclosed |