SCHEMBL33520

SCHEMBL33520

Nc1ccc([N+](=O)[O-])cc1[N+](=O)[O-]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 1.00
ALDH1A1 P00352 5/20 0.69
MAPT P10636 4/20 0.69
CYP3A4 P08684 3/20 0.69
MEN1 O00255 3/20 0.69
KMT2A Q03164 3/20 0.69
POLB P06746 1/20 0.69
ALOX15 P16050 1/20 0.69
TSHR P16473 3/20 0.64
GPR35 Q9HC97 3/20 0.61
MAPK1 P28482 2/20 0.61
TP53 P04637 1/20 0.61
HPGD P15428 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
HIF1A Q16665 1/20 0.61
TXNRD1 Q16881 1/20 0.59
TXNRD3 Q86VQ6 1/20 0.59
TXNRD2 Q9NNW7 1/20 0.59
GAA P10253 1/20 0.59
THRB P10828 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30293804 1.00 TDP1 (1.00) TDP1ALDH1A1MAPTCYP3A4MEN1
Nitrogen SCHEMBL27452981 0.96 TDP1 (0.92) TDP1ALDH1A1MAPTCYP3A4MEN1
Sulfuric Acid SCHEMBL28151771 0.90 TDP1 (0.81) TDP1ALDH1A1MAPTCYP3A4MEN1
SCHEMBL4938950 0.89 TDP1 (0.79) TDP1ALDH1A1MAPTCYP3A4MEN1
Dinitrochlorobenzene SCHEMBL28826452 0.89 TDP1 (0.79) TDP1ALDH1A1MAPTCYP3A4MEN1
SCHEMBL28339753 0.86 TDP1 (0.73) TDP1ALDH1A1MAPTCYP3A4MEN1
SCHEMBL18218196 0.85 TDP1 (0.74) TDP1ALDH1A1MAPTCYP3A4MEN1
SCHEMBL5489713 0.85 TDP1 (0.79) TDP1ALDH1A1MAPTCYP3A4MEN1
SCHEMBL2867570 0.84 TDP1 (0.73) TDP1ALDH1A1MAPTCYP3A4MEN1
SCHEMBL31553358 0.84 TDP1 (0.73) TDP1ALDH1A1MAPTCYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3432 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121801345-B Anti-ultraviolet dye with tannic acid as coupling component, and preparation method and application thereof 山东理工大学 2026-05-12 CN claimed
EP-4607278-A1 CHEMICALLY-AMPLIFIED POSITIVE PHOTORESIST COMPOSITION FOR PATTERN PROFILE IMPROVEMENT AND ETCH RESISTANCE ENHANCEMENT Ycchem Co., Ltd. (KR) 2025-08-27 EP claimed
US-20250199405-A1 CHEMICALLY-AMPLIFIED POSITIVE PHOTORESIST COMPOSITION FOR PATTERN PROFILE IMPROVEMENT AND ETCH RESISTANCE ENHANCEMENT YCCHEM CO., LTD. (KR) 2025-06-19 US claimed
CN-119998727-A Chemically amplified positive resist composition for improving pattern profile and enhancing etch resistance YC化学制品株式会社 2025-05-13 CN claimed
CN-114106341-B Comb copolymer, preparation method and application thereof 广州立邦涂料有限公司 2025-05-02 CN claimed
CN-119875390-A 3- [ [4- [ (2-R3) R4 amino-3-R2 ] phenyl ] azo ] -R1-nitrobenzene red dye and preparation method thereof 浙江大恒新材料有限公司 2025-04-25 CN claimed
CN-115836048-B Synthesis of N- (2, 4-dinitrophenyl) -4-nitrobenzamide (TNBA) using solid acid catalyst 杜邦安全与建筑公司 2025-04-18 CN claimed
CN-119819219-A Method and system for continuously producing 6-chloro-2, 4-dinitroaniline 浙江闰土研究院有限公司 2025-04-15 CN claimed
CN-119707773-A Preparation method and application of maleimide structure-containing compound 中国农业大学 2025-03-28 CN claimed
WO-2025034190-A1 STABILISED NICKELOPHILIC THIOSEMICARBAZONE COMPLEXES SHOWING SEMICONDUCTOR AND NONLINEAR OPTICAL PROPERTIES ISTANBUL UNIVERSITESI - CERRAHPASA REKTORLUGU (TR) 2025-02-13 WO claimed
US-4348389-A Quinoxaline adducts useful as anthelmintics INTERNATIONAL MINERALS & CHEMICAL CORP. (US) 1982-09-07 US claimed
EP-0049358-A1 Strontium and barium containing alkoxylation systems for unsaturated alcohols Conoco Phillips Company (US) 1982-04-14 EP claimed
EP-0046947-A1 Strontium and barium containing alkoxylation systems Conoco Phillips Company (US) 1982-03-10 EP claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
US-4213898-A FOR POLYACRYLONITRILE SANDOZ LTD. (CH) 1980-07-22 US claimed
US-4141917-A CARBOXYLIC ACID SOLVENTS HOECHST AKTIENGESELLSCHAFT (DE) 1979-02-27 US claimed
US-4102927-A Process for the preparation of 2,4-dinitroaniline HOECHST AKTIENGESELLSCHAFT (DE) 1978-07-25 US claimed
US-4097665-A Diacylnucleosides and process for preparing the same ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1978-06-27 US claimed
US-4011208-A 3-CYANO OR ACYL-4-ARYL-5-ARYLAZO-6-HYDROXYPYRIDONE-2 DYES SANDOZ LTD. (CH) 1977-03-08 US claimed
US-3998803-A TEXTILES FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) 1976-12-21 US claimed