⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33525751 | 0.92 | — | — | |
| SCHEMBL33525650 | 0.92 | — | — | |
| SCHEMBL33526032 | 0.91 | — | — | |
| SCHEMBL33525780 | 0.88 | — | — | |
| SCHEMBL33525775 | 0.87 | — | — | |
| SCHEMBL33525698 | 0.87 | — | — | |
| SCHEMBL33526325 | 0.86 | — | — | |
| SCHEMBL33525792 | 0.83 | — | — | |
| SCHEMBL33526409 | 0.83 | — | — | |
| SCHEMBL33525629 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12600733-B2 | KRAS inhibitors | ELI LILLY AND COMPANY (US) | 2026-04-14 | — | — | US | disclosed |
| US-20260092075-A1 | KRAS INHIBITORS | LILLY CO ELI (US) | 2026-04-02 | — | — | US | disclosed |