Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.41 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.41 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL521814 | 0.89 | HSD17B10 (0.49) | HSD17B10MAPTHDAC1TDP1TGFBR1 | |
| SCHEMBL2075907 | 0.88 | HSD17B10 (0.68) | HSD17B10MAPTHDAC1TDP1DRD2 | |
| SCHEMBL19848659 | 0.87 | MAPT (0.45) | HSD17B10MAPTMCHR1TDP1TGFBR1 | |
| SCHEMBL18731878 | 0.82 | HDAC1 (0.47) | HDAC1MCHR1TDP1TGFBR1TGFBR2 | |
| SCHEMBL17678353 | 0.82 | TSHR (0.48) | HSD17B10HDAC1MCHR1TDP1TGFBR1 | |
| SCHEMBL27835042 | 0.82 | HDAC1 (0.45) | HSD17B10HDAC1MCHR1TDP1TGFBR1 | |
| SCHEMBL24166800 | 0.80 | TNF (0.53) | HSD17B10MAPTTDP1DRD2DRD3 | |
| SCHEMBL30656804 | 0.80 | TNF (0.53) | HSD17B10MAPTTDP1DRD2DRD3 | |
| SCHEMBL3414135 | 0.79 | HDAC1 (0.53) | HSD17B10MAPTHDAC1MCHR1TDP1 | |
| SCHEMBL21025783 | 0.79 | KDM4E (0.48) | HDAC1MCHR1TDP1TGFBR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |