Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3352981 | 0.84 | GRM5 (0.41) | GRM5PDE10A | |
| SCHEMBL3347660 | 0.82 | KDM4E (0.31) | GRM5 | |
| SCHEMBL3347176 | 0.81 | GRM5 (0.40) | GRM5PDE10A | |
| SCHEMBL3347351 | 0.80 | SCN5A (0.31) | — | |
| SCHEMBL3351211 | 0.76 | GRM5 (0.56) | GRM5PDE10A | |
| SCHEMBL3347609 | 0.75 | GRM5 (0.33) | GRM5PDE10A | |
| SCHEMBL3347052 | 0.75 | CYP2A6 (0.37) | GRM5PDE10A | |
| SCHEMBL3347219 | 0.74 | GRM5 (0.37) | GRM5PDE10A | |
| SCHEMBL3345876 | 0.74 | GRM5 (0.53) | GRM5PDE10A | |
| SCHEMBL3347283 | 0.74 | CYP2A6 (0.36) | GRM5PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | claimed |
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |