Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.65 |
| ▸ | HTR2C | P28335 | 4/20 | 0.62 |
| ▸ | HTR6 | P50406 | 3/20 | 0.62 |
| ▸ | HTR2B | P41595 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2280381 | 0.79 | SLC6A4 (1.00) | SLC6A4HTR2CHTR6HTR2B | |
| SCHEMBL3347136 | 0.79 | SLC6A4 (0.65) | SLC6A4HTR2CHTR6HTR2B | |
| SCHEMBL12374665 | 0.77 | SLC6A4 (1.00) | SLC6A4HTR2CHTR6HTR2B | |
| SCHEMBL2282418 | 0.76 | SLC6A4 (0.72) | SLC6A4HTR2CHTR6HTR2B | |
| SCHEMBL2284573 | 0.76 | SLC6A4 (0.69) | SLC6A4HTR2CHTR2B | |
| SCHEMBL12374729 | 0.76 | SLC6A4 (0.77) | SLC6A4HTR2CHTR6HTR2B | |
| Hydrochloric Acid SCHEMBL2287844 | 0.75 | SLC6A4 (0.67) | SLC6A4HTR2CHTR2B | |
| SCHEMBL2288311 | 0.74 | SLC6A4 (0.76) | SLC6A4HTR2CHTR6HTR2B | |
| SCHEMBL13342757 | 0.74 | SMN1; SMN2 (0.55) | HTR2CHTR2B | |
| SCHEMBL2288732 | 0.74 | SLC6A4 (0.69) | SLC6A4HTR2CHTR6HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059393-A1 | SEROTONIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-05-27 | — | — | WO | disclosed |