Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 7/20 | 0.60 |
| ▸ | ACE | P12821 | 5/20 | 0.60 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.59 |
| ▸ | PSAT1 | Q9Y617 | 2/20 | 0.59 |
| ▸ | PPARG | P37231 | 8/20 | 0.57 |
| ▸ | PPARA | Q07869 | 6/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | KDM6B | O15054 | 1/20 | 0.55 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953468 | 0.87 | CYP1A2 (0.64) | SRRKDM6BPTGS1 | |
| SCHEMBL57558 | 0.87 | CYP1A2 (0.64) | SRRKDM6BPTGS1 | |
| SCHEMBL197252 | 0.87 | CYP1A2 (0.64) | SRRKDM6BPTGS1 | |
| SCHEMBL180366 | 0.87 | CYP1A2 (0.64) | SRRKDM6BPTGS1 | |
| SCHEMBL10891346 | 0.87 | KDM6B (0.67) | MMEACEKDM6BLMNATSHR | |
| SCHEMBL5800210 | 0.85 | CYP1A2 (0.61) | SRRKDM6BPTGS1 | |
| Hydrochloric Acid SCHEMBL1374834 | 0.85 | CYP1A2 (0.61) | SRRKDM6BPTGS1 | |
| Methane SCHEMBL3799102 | 0.85 | CYP1A2 (0.61) | SRRKDM6BPTGS1 | |
| Hydrochloric Acid SCHEMBL1374832 | 0.85 | CYP1A2 (0.61) | SRRKDM6BPTGS1 | |
| SCHEMBL11918359 | 0.85 | MME (0.67) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8883720-B2 | Template-fixed beta-hairpin peptidomimetics with CXCR4 antagonizing activity | POLYPHOR AG (CH) | 2014-11-11 | — | — | US | disclosed |
| US-20110312879-A1 | TEMPLATE-FIXED BETA-HAIRPIN PEPTIDOMIMETICS WITH CXCR4 ANTAGONIZING ACTIVITY | POLYPHOR AG (CH) | 2011-12-22 | — | — | US | disclosed |
| WO-2010060479-A1 | TEMPLATE-FIXED BETA-HAIRPIN PEPTIDOMIMETICS WITH CXCR4 ANTAGONIZING ACTIVITY | POLYPHOR AG (CH) | 2010-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110312879-A1 | TEMPLATE-FIXED BETA-HAIRPIN PEPTIDOMIMETICS WITH CXCR4 ANTAGONIZING ACTIVITY | CXCL12, CXCR4, CXCR1 | MME 383/4885ACE 2184/4885SRR 2229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.