Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 20/20 | 0.67 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3353682 | 1.00 | CALCRL (0.67) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL3355562 | 0.97 | CALCRL (0.70) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL3355571 | 0.97 | CALCRL (0.70) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL3354662 | 0.94 | CALCRL (0.71) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL3354728 | 0.94 | CALCRL (0.68) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL3354919 | 0.94 | CALCRL (0.68) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL3355496 | 0.92 | CALCRL (0.67) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL3353773 | 0.92 | CALCRL (0.69) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL3353786 | 0.92 | CALCRL (0.69) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL3353759 | 0.92 | CALCRL (0.71) | CALCRLRAMP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696195-B2 | Selected CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-13 | — | — | US | claimed |