Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16275180 | 0.94 | SLC7A5 (0.54) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL16275179 | 0.94 | SLC7A5 (0.54) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL8990000 | 0.88 | SLC7A5 (0.48) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL7163410 | 0.86 | SLC7A5 (0.58) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL7163413 | 0.86 | SLC7A5 (0.58) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL31530461 | 0.84 | SLC7A5 (0.53) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL10646229 | 0.82 | SLC1A3 (0.51) | SLC7A5TAAR1SLC6A2PTGS1ALPI | |
| SCHEMBL2172106 | 0.81 | SLC7A5 (0.49) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL2172100 | 0.81 | SLC7A5 (0.49) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL8712794 | 0.80 | SLC7A5 (0.59) | SLC7A5PTGS1ALPIPKMXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794663-A1 | PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF | Angiochem Inc. (CA) | 2014-10-29 | — | — | EP | disclosed |
| WO-2010063124-A1 | PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF | ANGIOCHEM INC. (CA) | 2010-06-10 | — | — | WO | disclosed |