Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 18/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7939905 | 0.84 | GRIA2 (0.64) | GRIA2CYP1A2CYP2C19 | |
| SCHEMBL2930121 | 0.80 | GRIA2 (0.74) | GRIA2CYP1A2CYP2C19 | |
| SCHEMBL2934808 | 0.79 | GRIA2 (0.73) | GRIA2CYP1A2CYP2C19 | |
| SCHEMBL2934244 | 0.77 | GRIA2 (1.00) | GRIA2CYP1A2CYP2C19 | |
| SCHEMBL2932604 | 0.77 | GRIA2 (1.00) | GRIA2CYP1A2CYP2C19 | |
| SCHEMBL2928683 | 0.77 | GRIA2 (0.70) | GRIA2CYP1A2CYP2C19 | |
| SCHEMBL15327105 | 0.77 | GRIA2 (0.54) | GRIA2CYP1A2CYP2C19 | |
| SCHEMBL11981812 | 0.77 | GRIA2 (0.54) | GRIA2CYP1A2CYP2C19 | |
| SCHEMBL3253671 | 0.76 | GRIA2 (1.00) | GRIA2CYP1A2CYP2C19 | |
| SCHEMBL3350022 | 0.76 | GRIA2 (0.57) | GRIA2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010066658-A1 | COMPOUNDS WHICH POTENTIATE THE AMPA RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2010-06-17 | — | — | WO | disclosed |
| WO-2010066658-A1 | COMPOUNDS WHICH POTENTIATE THE AMPA RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2010-06-17 | — | — | WO | disclosed |