Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | LTA4H | P09960 | 1/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14850009 | 0.95 | TDP1 (0.64) | TDP1LTA4HEPHX2MAPTRXFP1 | |
| SCHEMBL538370 | 0.95 | TDP1 (0.64) | TDP1LTA4HEPHX2MAPTRXFP1 | |
| SCHEMBL1006123 | 0.95 | TDP1 (0.64) | TDP1LTA4HEPHX2MAPTRXFP1 | |
| SCHEMBL1007046 | 0.95 | TDP1 (0.64) | TDP1LTA4HEPHX2MAPTRXFP1 | |
| SCHEMBL1006372 | 0.95 | TDP1 (0.64) | TDP1LTA4HEPHX2MAPTRXFP1 | |
| SCHEMBL1006938 | 0.95 | TDP1 (0.64) | TDP1LTA4HEPHX2MAPTRXFP1 | |
| SCHEMBL1005849 | 0.95 | TDP1 (0.64) | TDP1LTA4HEPHX2MAPTRXFP1 | |
| SCHEMBL1006585 | 0.95 | TDP1 (0.64) | TDP1LTA4HEPHX2MAPTRXFP1 | |
| SCHEMBL1006479 | 0.95 | TDP1 (0.64) | TDP1LTA4HEPHX2MAPTRXFP1 | |
| SCHEMBL405974 | 0.95 | TDP1 (0.64) | TDP1LTA4HEPHX2MAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2501761-B1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | SYMRISE AG (DE) | 2020-06-17 | — | — | EP | disclosed |
| EP-3663366-A2 | USE OF PHYSIOLOGICAL COOLING INGREDIENTS AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | Symrise AG (DE) | 2020-06-10 | — | — | EP | disclosed |
| EP-3434330-A1 | A METHOD FOR ENHANCING THE COOLING EFFECT OF A COOLING COMPOUND | Symrise AG (DE) | 2019-01-30 | — | — | EP | disclosed |
| EP-2394703-B1 | Cooling mixture with reinforced cooling effect of 5-methyl-2-(propan-2-yl)cyclohexyl-N-ethyloxamate | SYMRISE AG (DE) | 2015-12-23 | — | — | EP | disclosed |
| EP-2174645-B1 | Materials containing aromas incorporating cetyl nonanoate and/or stearyl nonanoate | SYMRISE AG (DE) | 2015-07-29 | — | — | EP | disclosed |
| EP-2394703-A1 | Cooling mixture with reinforced cooling effect of 5-methyl-2-(propan-2-yl)cyclohexyl-N-ethyloxamate | Symrise AG (DE) | 2011-12-14 | — | — | EP | disclosed |
| EP-2174645-A2 | Materials containing aromas incorporating cetyl nonanoate and/or stearyl nonanoate | Symrise GmbH & Co. KG (DE) | 2010-04-14 | — | — | EP | disclosed |
| EP-2158896-A2 | Materials containing aromas incorporating neopentyl glycol isononanoate | Symrise GmbH & Co. KG (DE) | 2010-03-03 | — | — | EP | disclosed |