Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 5/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 4/20 | 0.41 |
| ▸ | FLT3 | P36888 | 3/20 | 0.41 |
| ▸ | GAS6 | Q14393 | 3/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 2/20 | 0.36 |
| ▸ | CCND1 | P24385 | 2/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1604969 | 0.75 | SMN1; SMN2 (0.66) | MEN1KMT2AMAPK1HTTRAB9A | |
| SCHEMBL5171720 | 0.70 | FLT3 (0.40) | MERTKTYRO3FLT3GAS6EHMT2 | |
| SCHEMBL4226720 | 0.70 | FLT3 (0.40) | MERTKTYRO3FLT3GAS6EHMT2 | |
| SCHEMBL4222519 | 0.69 | FLT3 (0.40) | MERTKTYRO3FLT3GAS6EHMT2 | |
| SCHEMBL4690535 | 0.68 | CCR6 (0.47) | MERTKTYRO3FLT3GAS6OPRL1 | |
| SCHEMBL1089927 | 0.68 | CXCR4 (0.63) | EHMT2CDK4CCNE1CDK2ACHE | |
| SCHEMBL5171749 | 0.65 | FLT3 (0.41) | MERTKTYRO3FLT3GAS6MAPK1 | |
| SCHEMBL4220979 | 0.65 | FLT3 (0.41) | MERTKTYRO3FLT3GAS6MAPK1 | |
| SCHEMBL4220986 | 0.65 | FLT3 (0.41) | MERTKTYRO3FLT3GAS6MAPK1 | |
| SCHEMBL1089479 | 0.64 | CXCR4 (0.64) | CDK4CCNE1CDK2DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797099-B1 | PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS | EPIX DELAWARE INC (US) | 2010-08-11 | — | — | EP | disclosed |