Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.59 |
| ▸ | CTSD | P07339 | 3/20 | 0.59 |
| ▸ | CTSB | P07858 | 15/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13306013 | 1.00 | BACE1 (0.59) | BACE1CTSDCTSB | |
| SCHEMBL3356410 | 1.00 | BACE1 (0.59) | BACE1CTSDCTSB | |
| SCHEMBL3356422 | 1.00 | BACE1 (0.59) | BACE1CTSDCTSB | |
| SCHEMBL3352275 | 0.84 | BACE1 (0.76) | BACE1CTSDCTSB | |
| SCHEMBL3350377 | 0.84 | BACE1 (0.59) | BACE1CTSDCTSB | |
| SCHEMBL3352264 | 0.84 | BACE1 (0.76) | BACE1CTSDCTSB | |
| SCHEMBL3350386 | 0.84 | BACE1 (0.59) | BACE1CTSDCTSB | |
| SCHEMBL3351689 | 0.84 | BACE1 (0.67) | BACE1CTSDCTSB | |
| SCHEMBL3351683 | 0.84 | BACE1 (0.67) | BACE1CTSDCTSB | |
| SCHEMBL3358921 | 0.84 | BACE1 (0.73) | BACE1CTSDCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357766-A1 | PRIME EDITING GUIDE RNAS, COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | THE BROAD INSTITUTE, INC. (US) | 2023-11-09 | — | — | US | claimed |
| EP-4217490-A2 | PRIME EDITING GUIDE RNAS, COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | The Broad Institute Inc. (US) | 2023-08-02 | — | — | EP | claimed |
| US-20230357766-A1 | PRIME EDITING GUIDE RNAS, COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | THE BROAD INSTITUTE, INC. (US) | 2023-11-09 | — | — | US | disclosed |
| EP-4217490-A2 | PRIME EDITING GUIDE RNAS, COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | The Broad Institute Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| US-7727997-B2 | N,N′-substituted-1,3-diamino-2-hydroxypropane derivatives | ELAN PHARMACEUTICALS, INC. (US) | 2010-06-01 | — | — | US | disclosed |
| US-20070249820-A1 | Activatable Ribozymal Purification Constructs and Methods of Use | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2007-10-25 | — | — | US | disclosed |
| US-7176242-B2 | N,N′-substituted-1,3-diamino-2-hydroxypropane derivatives | ELAN PHARMACEUTICALS, INC. (US) | 2007-02-13 | — | — | US | disclosed |
| WO-2005067665-A2 | ACTIVATABLE RIBOZYMAL PURIFICATION CONSTRUCTS AND METHODS OF USE | UNIVERSITY OF COLORADO (US) | 2005-07-28 | — | — | WO | disclosed |