Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | COMT | P21964 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ESRRG | P62508 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336083 | 0.88 | F9 (0.41) | METAP2SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL336996 | 0.87 | MEN1 (0.44) | SMN1; SMN2MAPTMEN1KMT2AESRRG | |
| SCHEMBL337002 | 0.85 | MAPT (0.41) | SMN1; SMN2MAPTESRRGCNR2 | |
| SCHEMBL335484 | 0.84 | MAPT (0.43) | SMN1; SMN2MAPTCNR2 | |
| SCHEMBL335283 | 0.84 | MAPT (0.37) | SMN1; SMN2MAPTMEN1KMT2AESRRG | |
| SCHEMBL335848 | 0.83 | MCHR1 (0.42) | SMN1; SMN2MAPTESRRG | |
| SCHEMBL334843 | 0.81 | KDR (0.45) | COMTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL335303 | 0.81 | MAPT (0.40) | SMN1; SMN2MAPTESRRG | |
| SCHEMBL336055 | 0.81 | MAPT (0.46) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL335968 | 0.80 | MAPT (0.41) | RAB9ASMN1; SMN2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069289-B1 | ISOSERINE DERIVATIVES FOR USE AS COAGULATION FACTOR IXa INHIBITORS | SANOFI SA (FR) | 2013-10-02 | — | — | EP | claimed |
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | claimed |
| US-20090233949-A1 | ISOSERINE DERIVATIVES FOR USE AS COAGULATION FACTOR IXA INHIBITORS | SANOFI-AVENTIS (FR) | 2009-09-17 | — | — | US | claimed |
| CN-101516834-A | Isoserine derivatives for use as coagulation factor ixa inhibitors | SANOFI AVENTIS (FR) | 2009-08-26 | — | — | CN | claimed |
| CN-1359423-A | Herbicide resistant plants | HINZENTA CO LTD (GB) | 2002-07-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233949-A1 | ISOSERINE DERIVATIVES FOR USE AS COAGULATION FACTOR IXA INHIBITORS | TFPI, F2, F9 | METAP2 1005/4885COMT 4308/4885NPC1 2621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.