Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3355999 | 0.97 | TLR7 (0.51) | TLR7KDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL3356920 | 0.96 | TLR7 (0.53) | TLR7KDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL3436183 | 0.94 | TLR7 (0.53) | TLR7KDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL3359719 | 0.94 | TLR7 (0.53) | TLR7KDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL2195843 | 0.90 | TLR7 (0.57) | TLR7KDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL2198970 | 0.89 | TLR7 (0.61) | TLR7KDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL2198572 | 0.88 | TLR7 (0.65) | TLR7KDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL2197783 | 0.87 | TLR7 (0.58) | TLR7 | |
| SCHEMBL3355766 | 0.86 | TLR7 (0.51) | TLR7 | |
| SCHEMBL2197633 | 0.86 | TLR7 (0.62) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018132-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2010-02-18 | — | — | WO | disclosed |