SCHEMBL3358113

SCHEMBL3358113

CCOC(=O)COc1ccc(/C=C/c2cc(OC)cc(OC)c2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.68
AHR P35869 3/20 0.68
FFAR1 O14842 2/20 0.60
PPARG P37231 2/20 0.60
PPARD Q03181 2/20 0.60
PPARA Q07869 2/20 0.60
GAA P10253 2/20 0.57
NPSR1 Q6W5P4 1/20 0.57
PTGS2 P35354 3/20 0.57
ABL1 P00519 3/20 0.57
ABCB1 P08183 3/20 0.57
BCR P11274 3/20 0.57
TTR P02766 2/20 0.57
CYP1A1 P04798 2/20 0.57
ALOX5 P09917 2/20 0.57
NQO2 P16083 2/20 0.57
CYP1B1 Q16678 2/20 0.57
CYP1A2 P05177 1/20 0.57
CYP19A1 P11511 1/20 0.57
TUBB4A P04350 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3358118 1.00 ESR1 (0.68) ESR1AHRFFAR1PPARGPPARD
SCHEMBL20024754 0.88 GAA (0.66) GAANPSR1PTGS2CYP1A2KDM4E
SCHEMBL3362005 0.84 PPARG (0.81) ESR1AHRFFAR1PPARGPPARD
SCHEMBL3362007 0.84 PPARG (0.81) ESR1AHRFFAR1PPARGPPARD
SCHEMBL1573002 0.83 SMN1; SMN2 (0.55) PPARGPPARAGAANPSR1CYP1A2
SCHEMBL5356914 0.83 SMN1; SMN2 (0.55) PPARGPPARAGAANPSR1CYP1A2
SCHEMBL435444 0.83 GAA (0.68) GAANPSR1KDM4EMEN1MAPT
SCHEMBL28400207 0.83 HDAC3 (0.72) ESR1AHRFFAR1PPARGPPARD
SCHEMBL28397027 0.83 HDAC3 (0.72) ESR1AHRFFAR1PPARGPPARD
SCHEMBL20024726 0.82 GAA (0.59) GAANPSR1PTGS2CYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010046926-A2 NOVEL STILBENE ANALOGS APTUIT LAURUS PVT LTD (IN) 2010-04-29 WO claimed
WO-2010046926-A2 NOVEL STILBENE ANALOGS APTUIT LAURUS PVT LTD (IN) 2010-04-29 WO disclosed