Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 14/20 | 0.54 |
| ▸ | CNR1 | P21554 | 3/20 | 0.54 |
| ▸ | CNR2 | P34972 | 2/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1605161 | 0.82 | MEN1 (0.64) | MEN1CNR1CNR2HTR2BKMT2A | |
| SCHEMBL1604017 | 0.81 | HTR2B (0.67) | MEN1HTR2BKMT2AHTTSMN1; SMN2 | |
| SCHEMBL13060028 | 0.79 | MEN1 (0.66) | MEN1HTR2BKMT2AHTTSMN1; SMN2 | |
| SCHEMBL1604665 | 0.78 | MEN1 (0.61) | MEN1CNR1CNR2HTR2BKMT2A | |
| SCHEMBL1604944 | 0.78 | MEN1 (0.61) | MEN1CNR1CNR2HTR2BKMT2A | |
| SCHEMBL1604029 | 0.78 | CNR1 (0.64) | MEN1CNR1CNR2HTR2BKMT2A | |
| SCHEMBL1604955 | 0.77 | HTR2B (0.70) | MEN1CNR1HTR2BKMT2AHTT | |
| SCHEMBL1604180 | 0.77 | MEN1 (0.60) | MEN1CNR1CNR2HTR2BKMT2A | |
| SCHEMBL1604829 | 0.76 | MEN1 (0.61) | MEN1HTR2BKMT2AHTTSMN1; SMN2 | |
| SCHEMBL1604148 | 0.76 | HTR2B (0.70) | MEN1HTR2BKMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797099-B1 | PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS | EPIX DELAWARE INC (US) | 2010-08-11 | — | — | EP | claimed |