Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL221807 | 1.00 | — | — | |
| Bicarbonate SCHEMBL367438 | 1.00 | — | — | |
| Bicarbonate SCHEMBL18280934 | 0.94 | — | — | |
| Bicarbonate SCHEMBL31512405 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL30978003 | 0.94 | — | — | |
| Bicarbonate SCHEMBL6528412 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL7627649 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1829439 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL408953 | 0.94 | — | — | |
| Bicarbonate SCHEMBL28972021 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4056899-B1 | ROTARY GRATE WITH A FUEL-INDEPENDENT CLEANING DEVICE FOR A BIOMASSE HEATING SYSTEM AND METHOD FOR CLEANING THE GRATE | SL TECHNIK GMBH (AT) | 2023-07-05 | — | — | EP | disclosed |
| CN-114969665-B | Method and system for estimating carbon emission and carbon reserve of mineral resource base | 中国地质科学院矿产资源研究所 | 2023-02-10 | — | — | CN | disclosed |
| CN-114969665-A | Method and system for estimating carbon emission and carbon reserve of mineral resource base | 中国地质科学院矿产资源研究所 | 2022-08-30 | — | — | CN | disclosed |
| US-20100280218-A1 | POLYMERIC MATERIALS FROM RENEWABLE RESOURCES | WAGENER EARL H | 2010-11-04 | — | — | US | disclosed |
| US-7723461-B1 | Polymeric materials from renewable resources | TETRAMER TECHNOLOGIES, LLC | 2010-05-25 | — | — | US | disclosed |