Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 3/20 | 0.78 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.78 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.45 |
| ▸ | KIF11 | P52732 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3359165 | 1.00 | SCN5A (0.78) | SCN5ASCN9AEPHX1KIF11EPHX2 | |
| SCHEMBL1712517 | 0.88 | SCN5A (1.00) | SCN5ASCN9AEPHX1KIF11EPHX2 | |
| SCHEMBL1712264 | 0.88 | SCN5A (1.00) | SCN5ASCN9AEPHX1KIF11EPHX2 | |
| SCHEMBL1712454 | 0.88 | SCN5A (1.00) | SCN5ASCN9AEPHX1KIF11EPHX2 | |
| SCHEMBL10357746 | 0.85 | SCN5A (0.55) | SCN5ASCN9AKIF11 | |
| SCHEMBL12315579 | 0.85 | SCN5A (0.55) | SCN5ASCN9AKIF11 | |
| SCHEMBL5155798 | 0.85 | SCN5A (0.55) | SCN5ASCN9AKIF11 | |
| SCHEMBL8667621 | 0.85 | SCN5A (0.55) | SCN5ASCN9AKIF11 | |
| SCHEMBL29211112 | 0.85 | SCN5A (0.55) | SCN5ASCN9AKIF11 | |
| SCHEMBL7916110 | 0.85 | SCN5A (0.55) | SCN5ASCN9AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010027641-A2 | NA CHANNELS, DISEASE, AND RELATED ASSAYS AND COMPOSITIONS | GEORGETOWN UNIVERSITY (US) | 2010-03-11 | — | — | WO | disclosed |