SCHEMBL3359207

SCHEMBL3359207

CCN(CC)CC.NC(=O)c1sc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)nc1N

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SCD O00767 16/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3336698 0.93 SCD (0.70) SCD
SCHEMBL13638368 0.79 SCD (0.64) SCD
SCHEMBL4622608 0.76 SCD (0.62) SCD
SCHEMBL472976 0.76 SCD (1.00) SCD
SCHEMBL4510390 0.75 SCD (0.59) SCD
SCHEMBL3338886 0.75 SCD (0.53) SCD
SCHEMBL3337360 0.74 SCD (0.60) SCD
SCHEMBL4505452 0.72 SCD (0.69) SCD
SCHEMBL473029 0.72 SCD (0.73) SCD
SCHEMBL4092010 0.72 SCD (0.80) SCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2152719-A1 BICYCLIC HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE Merck Frosst Canada Ltd. (CA) 2010-02-17 EP disclosed
WO-2008141455-A1 BICYCLIC HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE MERCK FROSST CANADA LTD. (CA) 2008-11-27 WO disclosed