Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZAP70 | P43403 | 17/20 | 0.58 |
| ▸ | SYK | P43405 | 2/20 | 0.40 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1048396 | 0.90 | ZAP70 (0.58) | ZAP70SYK | |
| SCHEMBL1045554 | 0.85 | ZAP70 (0.65) | ZAP70SYK | |
| SCHEMBL1048294 | 0.83 | ZAP70 (0.62) | ZAP70SYK | |
| SCHEMBL1047735 | 0.83 | ZAP70 (0.79) | ZAP70SYK | |
| SCHEMBL3362102 | 0.83 | SYK (0.39) | ZAP70SYKMAP4K1 | |
| SCHEMBL1046853 | 0.78 | ZAP70 (0.68) | ZAP70SYK | |
| SCHEMBL1047250 | 0.78 | ZAP70 (0.58) | ZAP70 | |
| SCHEMBL1049792 | 0.77 | ZAP70 (0.57) | ZAP70 | |
| SCHEMBL1049379 | 0.77 | ZAP70 (0.59) | ZAP70 | |
| SCHEMBL1043245 | 0.77 | ZAP70 (0.66) | ZAP70SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238137-A1 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | IRM LLC (BM) | 2010-10-13 | — | — | EP | claimed |
| WO-2009097287-A1 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | IRM LLC (BM) | 2009-08-06 | — | — | WO | claimed |