Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361547 | 0.93 | BACE1 (0.38) | BACE1KCNH2 | |
| SCHEMBL3359098 | 0.80 | BACE1 (0.39) | BACE1KCNH2 | |
| SCHEMBL3358864 | 0.79 | BACE1 (0.57) | BACE1KCNH2 | |
| SCHEMBL3357632 | 0.76 | BACE1 (0.52) | BACE1KCNH2 | |
| SCHEMBL3357423 | 0.76 | BACE1 (0.39) | BACE1KCNH2 | |
| SCHEMBL3777038 | 0.73 | BACE1 (0.46) | BACE1KCNH2 | |
| Trifluoroacetic Acid SCHEMBL2086620 | 0.71 | BACE1 (0.55) | BACE1KCNH2 | |
| SCHEMBL3361552 | 0.70 | — | — | |
| Trifluoroacetic Acid SCHEMBL3243544 | 0.69 | BACE1 (0.42) | BACE1KCNH2 | |
| SCHEMBL3769867 | 0.69 | BACE1 (0.49) | BACE1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100125081-A1 | NEW COMPOUNDS 574 | ASTRAZENECA AB (SE) | 2010-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100125081-A1 | NEW COMPOUNDS 574 | PSEN1, PSEN2, BACE1 | BACE1 3/4885KCNH2 4727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.